Tawfik DS - Search Results

1

Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series.

Khersonsky O, Röthlisberger D, Dym O, Albeck S, Jackson CJ, Baker D, Tawfik DS. Khersonsky O, et al. Among authors: tawfik ds. J Mol Biol. 2010 Mar 5;396(4):1025-42. doi: 10.1016/j.jmb.2009.12.031. Epub 2009 Dec 28. J Mol Biol. 2010. PMID: 20036254

2

Expression and characterization of recombinant single-chain Fv and Fv fragments derived from a set of catalytic antibodies.

Kim SH, Schindler DG, Lindner AB, Tawfik DS, Eshhar Z. Kim SH, et al. Among authors: tawfik ds. Mol Immunol. 1997 Aug-Sep;34(12-13):891-906. doi: 10.1016/s0161-5890(97)00096-5. Mol Immunol. 1997. PMID: 9464525

3

Conformational changes affect binding and catalysis by ester-hydrolysing antibodies.

Lindner AB, Eshhar Z, Tawfik DS. Lindner AB, et al. Among authors: tawfik ds. J Mol Biol. 1999 Jan 8;285(1):421-30. doi: 10.1006/jmbi.1998.2309. J Mol Biol. 1999. PMID: 9878416

4

Esterolytic antibodies as mechanistic and structural models of hydrolases-a quantitative analysis.

Lindner AB, Kim SH, Schindler DG, Eshhar Z, Tawfik DS. Lindner AB, et al. Among authors: tawfik ds. J Mol Biol. 2002 Jul 12;320(3):559-72. doi: 10.1016/s0022-2836(02)00418-7. J Mol Biol. 2002. PMID: 12096909

5

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.

Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Harel M, et al. Among authors: tawfik ds. Nat Struct Mol Biol. 2004 May;11(5):412-9. doi: 10.1038/nsmb767. Epub 2004 Apr 18. Nat Struct Mol Biol. 2004. PMID: 15098021

6

The 'evolvability' of promiscuous protein functions.

Aharoni A, Gaidukov L, Khersonsky O, McQ Gould S, Roodveldt C, Tawfik DS. Aharoni A, et al. Among authors: tawfik ds. Nat Genet. 2005 Jan;37(1):73-6. doi: 10.1038/ng1482. Epub 2004 Nov 28. Nat Genet. 2005. PMID: 15568024

7

Directed evolution of protein inhibitors of DNA-nucleases by in vitro compartmentalization (IVC) and nano-droplet delivery.

Bernath K, Magdassi S, Tawfik DS. Bernath K, et al. Among authors: tawfik ds. J Mol Biol. 2005 Feb 4;345(5):1015-26. doi: 10.1016/j.jmb.2004.11.017. Epub 2004 Dec 7. J Mol Biol. 2005. PMID: 15644201

8

Directed evolution of proteins for heterologous expression and stability.

Roodveldt C, Aharoni A, Tawfik DS. Roodveldt C, et al. Among authors: tawfik ds. Curr Opin Struct Biol. 2005 Feb;15(1):50-6. doi: 10.1016/j.sbi.2005.01.001. Curr Opin Struct Biol. 2005. PMID: 15718133 Review.

9

High-throughput screens and selections of enzyme-encoding genes.

Aharoni A, Griffiths AD, Tawfik DS. Aharoni A, et al. Among authors: tawfik ds. Curr Opin Chem Biol. 2005 Apr;9(2):210-6. doi: 10.1016/j.cbpa.2005.02.002. Curr Opin Chem Biol. 2005. PMID: 15811807 Review.

10

Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.

Khersonsky O, Tawfik DS. Khersonsky O, et al. Among authors: tawfik ds. Biochemistry. 2005 Apr 26;44(16):6371-82. doi: 10.1021/bi047440d. Biochemistry. 2005. PMID: 15835926

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