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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: wouters bg. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
Modulation of cell death in the tumor microenvironment.
Wouters BG, Koritzinsky M, Chiu RK, Theys J, Buijsen J, Lambin P. Wouters BG, et al. Semin Radiat Oncol. 2003 Jan;13(1):31-41. doi: 10.1053/srao.2003.50004. Semin Radiat Oncol. 2003. PMID: 12520462 Review.
Targeting hypoxia tolerance in cancer.
Wouters BG, van den Beucken T, Magagnin MG, Lambin P, Koumenis C. Wouters BG, et al. Drug Resist Updat. 2004 Feb;7(1):25-40. doi: 10.1016/j.drup.2003.12.004. Drug Resist Updat. 2004. PMID: 15072769 Review.
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.
Koritzinsky M, Magagnin MG, van den Beucken T, Seigneuric R, Savelkouls K, Dostie J, Pyronnet S, Kaufman RJ, Weppler SA, Voncken JW, Lambin P, Koumenis C, Sonenberg N, Wouters BG. Koritzinsky M, et al. Among authors: wouters bg. EMBO J. 2006 Mar 8;25(5):1114-25. doi: 10.1038/sj.emboj.7600998. Epub 2006 Feb 9. EMBO J. 2006. PMID: 16467844 Free PMC article.
234 results