Akaho E - Search Results

1

A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors.

Ali HI, Fujita T, Akaho E, Nagamatsu T. Ali HI, et al. Among authors: akaho e. J Comput Aided Mol Des. 2010 Jan;24(1):57-75. doi: 10.1007/s10822-009-9314-z. Epub 2009 Dec 29. J Comput Aided Mol Des. 2010. PMID: 20039101

2

Antitumor studies -- part 2: structure-activity relationship study for flavin analogs including investigations on their in vitro antitumor assay and docking simulation into protein tyrosine kinase.

Ali HI, Tomita K, Akaho E, Kunishima M, Kawashima Y, Yamagishi T, Ikeya H, Nagamatsu T. Ali HI, et al. Among authors: akaho e. Eur J Med Chem. 2008 Jul;43(7):1376-89. doi: 10.1016/j.ejmech.2007.10.011. Epub 2007 Oct 14. Eur J Med Chem. 2008. PMID: 18055068

3

Antitumor studies. Part 1: design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents.

Ali HI, Tomita K, Akaho E, Kambara H, Miura S, Hayakawa H, Ashida N, Kawashima Y, Yamagishi T, Ikeya H, Yoneda F, Nagamatsu T. Ali HI, et al. Among authors: akaho e. Bioorg Med Chem. 2007 Jan 1;15(1):242-56. doi: 10.1016/j.bmc.2006.09.063. Epub 2006 Sep 30. Bioorg Med Chem. 2007. PMID: 17049252 Free article.

4

Studies on 16α-Hydroxylation of Steroid Molecules and Regioselective Binding Mode in Homology-Modeled Cytochrome P450-2C11.

Ali HI, Yamada M, Fujita Y, Maeda M, Akaho E. Ali HI, et al. Among authors: akaho e. Int J Med Chem. 2011;2011:918168. doi: 10.1155/2011/918168. Epub 2010 Jul 27. Int J Med Chem. 2011. PMID: 27516905 Free PMC article.

5

Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.

Zheng X, Oda H, Takamatsu K, Sugimoto Y, Tai A, Akaho E, Ali HI, Oshiki T, Kakuta H, Sasaki K. Zheng X, et al. Among authors: akaho e. Bioorg Med Chem. 2007 Jan 15;15(2):1014-21. doi: 10.1016/j.bmc.2006.10.029. Epub 2006 Oct 18. Bioorg Med Chem. 2007. PMID: 17079150

6

Structure-based drug design and AutoDock study of potential protein tyrosine kinase inhibitors.

Ali HI, Nagamatsu T, Akaho E. Ali HI, et al. Among authors: akaho e. Bioinformation. 2011 Feb 7;5(9):368-74. doi: 10.6026/97320630005368. Bioinformation. 2011. PMID: 21383902 Free PMC article.

7

Reduction of lipophilicity at the lipophilic domain of RXR agonists enables production of subtype preference: RXRalpha-preferential agonist possessing a sulfonamide moiety.

Takamatsu K, Takano A, Yakushiji N, Morishita K, Matsuura N, Makishima M, Ali HI, Akaho E, Tai A, Sasaki K, Kakuta H. Takamatsu K, et al. Among authors: akaho e. ChemMedChem. 2008 Mar;3(3):454-60. doi: 10.1002/cmdc.200700265. ChemMedChem. 2008. PMID: 18157857

8

A study on medicinal plants from Malaysia focused on Acalypha siamensis Oliv. ex Gage. isolation and structure of a new tetraterpene, acalyphaser A.

Kambara H, Yamada T, Tsujioka M, Matsunaga S, Tanaka R, Ali HI, Wiart C, Yusof M, Hassan H, Hanifah A, Fauzi ZM, Mazlan NH, Jay M, Kunishima M, Akaho E. Kambara H, et al. Among authors: akaho e. Chem Biodivers. 2006 Dec;3(12):1301-6. doi: 10.1002/cbdv.200690133. Chem Biodivers. 2006. PMID: 17193244

9

Evaluation of indole esters as inhibitors of p60(c-Src) receptor tyrosine kinase and investigation of the inhibition using receptor docking studies.

Olgen S, Akaho E, Nebioglu D. Olgen S, et al. Among authors: akaho e. J Enzyme Inhib Med Chem. 2003 Dec;18(6):485-90. doi: 10.1080/14756360310001612211. J Enzyme Inhib Med Chem. 2003. PMID: 15008512 Free article.

10

Synthesis and anti-tyrosine kinase activity of 3-(substituted-benzylidene)-1, 3-dihydro-indolin derivatives: investigation of their role against p60c-Src receptor tyrosine kinase with the application of receptor docking studies.

Olgen S, Akaho E, Nebioglu D. Olgen S, et al. Among authors: akaho e. Farmaco. 2005 Jun-Jul;60(6-7):497-506. doi: 10.1016/j.farmac.2005.01.015. Farmaco. 2005. PMID: 15927182

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