Neschen S - Search Results

1

High-fat, carbohydrate-free diet markedly aggravates obesity but prevents beta-cell loss and diabetes in the obese, diabetes-susceptible db/db strain.

Mirhashemi F, Kluth O, Scherneck S, Vogel H, Kluge R, Schurmann A, Joost HG, Neschen S. Mirhashemi F, et al. Among authors: neschen s. Obes Facts. 2008;1(6):292-7. doi: 10.1159/000176064. Epub 2008 Dec 2. Obes Facts. 2008. PMID: 20054191 Free PMC article.

2

Development of diabetes in obese, insulin-resistant mice: essential role of dietary carbohydrate in beta cell destruction.

Jürgens HS, Neschen S, Ortmann S, Scherneck S, Schmolz K, Schüler G, Schmidt S, Blüher M, Klaus S, Perez-Tilve D, Tschöp MH, Schürmann A, Joost HG. Jürgens HS, et al. Among authors: neschen s. Diabetologia. 2007 Jul;50(7):1481-9. doi: 10.1007/s00125-007-0662-8. Epub 2007 Apr 17. Diabetologia. 2007. PMID: 17437079

3

Diet dependence of diabetes in the New Zealand Obese (NZO) mouse: total fat, but not fat quality or sucrose accelerates and aggravates diabetes.

Mirhashemi F, Scherneck S, Kluth O, Kaiser D, Vogel H, Kluge R, Schürmann A, Neschen S, Joost HG. Mirhashemi F, et al. Among authors: neschen s. Exp Clin Endocrinol Diabetes. 2011 Mar;119(3):167-71. doi: 10.1055/s-0030-1263127. Epub 2010 Sep 8. Exp Clin Endocrinol Diabetes. 2011. PMID: 20827663

4

Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.

Kluth O, Mirhashemi F, Scherneck S, Kaiser D, Kluge R, Neschen S, Joost HG, Schürmann A. Kluth O, et al. Among authors: neschen s. Diabetologia. 2011 Mar;54(3):605-16. doi: 10.1007/s00125-010-1973-8. Epub 2010 Nov 24. Diabetologia. 2011. PMID: 21107520 Free PMC article.

5

Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity.

Buchmann J, Meyer C, Neschen S, Augustin R, Schmolz K, Kluge R, Al-Hasani H, Jürgens H, Eulenberg K, Wehr R, Dohrmann C, Joost HG, Schürmann A. Buchmann J, et al. Among authors: neschen s. Endocrinology. 2007 Apr;148(4):1561-73. doi: 10.1210/en.2006-1244. Epub 2006 Dec 28. Endocrinology. 2007. PMID: 17194745

6

Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo.

Neschen S, Katterle Y, Richter J, Augustin R, Scherneck S, Mirhashemi F, Schürmann A, Joost HG, Klaus S. Neschen S, et al. Physiol Genomics. 2008 May 13;33(3):333-40. doi: 10.1152/physiolgenomics.00226.2007. Epub 2008 Mar 18. Physiol Genomics. 2008. PMID: 18349383

7

The central melanocortin system directly controls peripheral lipid metabolism.

Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. Among authors: neschen s. J Clin Invest. 2007 Nov;117(11):3475-88. doi: 10.1172/JCI31743. J Clin Invest. 2007. PMID: 17885689 Free PMC article.

8

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.

Hammond LE, Neschen S, Romanelli AJ, Cline GW, Ilkayeva OR, Shulman GI, Muoio DM, Coleman RA. Hammond LE, et al. Among authors: neschen s. J Biol Chem. 2005 Jul 8;280(27):25629-36. doi: 10.1074/jbc.M503181200. Epub 2005 May 6. J Biol Chem. 2005. PMID: 15878874 Free article.

9

Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet.

Walker A, Pfitzner B, Neschen S, Kahle M, Harir M, Lucio M, Moritz F, Tziotis D, Witting M, Rothballer M, Engel M, Schmid M, Endesfelder D, Klingenspor M, Rattei T, Castell WZ, de Angelis MH, Hartmann A, Schmitt-Kopplin P. Walker A, et al. Among authors: neschen s. ISME J. 2014 Dec;8(12):2380-96. doi: 10.1038/ismej.2014.79. Epub 2014 Jun 6. ISME J. 2014. PMID: 24906017 Free PMC article.

10

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M. Franko A, et al. Among authors: neschen s. Diabetes. 2016 Sep;65(9):2540-52. doi: 10.2337/db15-1670. Epub 2016 Jun 9. Diabetes. 2016. PMID: 27284107

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