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A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
van der Bol JM, Mathijssen RH, Creemers GJ, Planting AS, Loos WJ, Wiemer EA, Friberg LE, Verweij J, Sparreboom A, de Jong FA. van der Bol JM, et al. Among authors: mathijssen rh. Clin Cancer Res. 2010 Jan 15;16(2):736-42. doi: 10.1158/1078-0432.CCR-09-1526. Epub 2010 Jan 12. Clin Cancer Res. 2010. PMID: 20068078 Clinical Trial.
Irinotecan (CPT-11) metabolism and disposition in cancer patients.
Sparreboom A, de Jonge MJ, de Bruijn P, Brouwer E, Nooter K, Loos WJ, van Alphen RJ, Mathijssen RH, Stoter G, Verweij J. Sparreboom A, et al. Among authors: mathijssen rh. Clin Cancer Res. 1998 Nov;4(11):2747-54. Clin Cancer Res. 1998. PMID: 9829738 Clinical Trial.
Modulation of irinotecan metabolism by ketoconazole.
Kehrer DF, Mathijssen RH, Verweij J, de Bruijn P, Sparreboom A. Kehrer DF, et al. Among authors: mathijssen rh. J Clin Oncol. 2002 Jul 15;20(14):3122-9. doi: 10.1200/JCO.2002.08.177. J Clin Oncol. 2002. PMID: 12118026 Clinical Trial.
421 results