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A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.
Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD. Keller MP, et al. Among authors: davis db. Genome Res. 2008 May;18(5):706-16. doi: 10.1101/gr.074914.107. Epub 2008 Mar 17. Genome Res. 2008. PMID: 18347327 Free PMC article.
Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function.
Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Lavine JA, et al. Among authors: davis db. Mol Endocrinol. 2008 Dec;22(12):2716-28. doi: 10.1210/me.2008-0255. Epub 2008 Oct 9. Mol Endocrinol. 2008. Retraction in: Mol Endocrinol. 2010 Feb;24(2):472. doi: 10.1210/mend.24.2.9999 PMID: 18845673 Free PMC article. Retracted.
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.
Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Lavine JA, et al. Among authors: davis db. Endocrinology. 2010 Aug;151(8):3577-88. doi: 10.1210/en.2010-0233. Epub 2010 Jun 9. Endocrinology. 2010. PMID: 20534724 Free PMC article.
FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. Davis DB, et al. Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082. Epub 2010 Jul 21. Mol Endocrinol. 2010. PMID: 20660304 Free PMC article.
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.
Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Krautkramer KA, et al. Among authors: davis db. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E600-10. doi: 10.1152/ajpendo.00147.2013. Epub 2013 Jul 16. Am J Physiol Endocrinol Metab. 2013. PMID: 23860123 Free PMC article.
Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis.
Lavine JA, Kibbe CR, Baan M, Sirinvaravong S, Umhoefer HM, Engler KA, Meske LM, Sacotte KA, Erhardt DP, Davis DB. Lavine JA, et al. Among authors: davis db. Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E819-28. doi: 10.1152/ajpendo.00159.2015. Epub 2015 Sep 22. Am J Physiol Endocrinol Metab. 2015. PMID: 26394663 Free PMC article.
What the BTBR/J mouse has taught us about diabetes and diabetic complications.
Keller MP, Hudkins KL, Shalev A, Bhatnagar S, Kebede MA, Merrins MJ, Davis DB, Alpers CE, Kimple ME, Attie AD. Keller MP, et al. Among authors: davis db. iScience. 2023 Jun 7;26(7):107036. doi: 10.1016/j.isci.2023.107036. eCollection 2023 Jul 21. iScience. 2023. PMID: 37360692 Free PMC article. Review.
96 results