Gan J - Search Results

1

Mechanism-based inhibition of human cytochrome P4503A4 by domperidone.

Chang SY, Fancher RM, Zhang H, Gan J. Chang SY, et al. Among authors: gan j. Xenobiotica. 2010 Feb;40(2):138-45. doi: 10.3109/00498250903406762. Xenobiotica. 2010. PMID: 20082577

2

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.

Gu X, Wang L, Gan J, Fancher RM, Tian Y, Hong Y, Lai Y, Sinz M, Shen H. Gu X, et al. Among authors: gan j. Drug Metab Dispos. 2020 Aug;48(8):724-734. doi: 10.1124/dmd.120.090670. Epub 2020 Jun 1. Drug Metab Dispos. 2020. PMID: 32482623

3

Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents.

Rohrbach KW, Han S, Gan J, O'Tanyi EJ, Zhang H, Chi CL, Taub R, Largent BL, Cheng D. Rohrbach KW, et al. Among authors: gan j. Eur J Pharmacol. 2005 Mar 21;511(1):31-41. doi: 10.1016/j.ejphar.2005.01.034. Eur J Pharmacol. 2005. PMID: 15777777

4

Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism.

Gan J, Chen W, Shen H, Gao L, Hong Y, Tian Y, Li W, Zhang Y, Tang Y, Zhang H, Humphreys WG, Rodrigues AD. Gan J, et al. Br J Clin Pharmacol. 2010 Dec;70(6):870-80. doi: 10.1111/j.1365-2125.2010.03772.x. Br J Clin Pharmacol. 2010. PMID: 21175442 Free PMC article.

5

Drug-Protein Adducts: Chemistry, Mechanisms of Toxicity, and Methods of Characterization.

Gan J, Zhang H, Humphreys WG. Gan J, et al. Chem Res Toxicol. 2016 Dec 19;29(12):2040-2057. doi: 10.1021/acs.chemrestox.6b00274. Epub 2016 Dec 5. Chem Res Toxicol. 2016. PMID: 27989144 Review.

6

High-resolution mass spectrometry-based background subtraction for identifying protein modifications in a complex biological system: detection of acetaminophen-bound microsomal proteins including argininosuccinate synthetase.

Zhang H, Gan J, Shu YZ, Humphreys WG. Zhang H, et al. Among authors: gan j. Chem Res Toxicol. 2015 Apr 20;28(4):775-81. doi: 10.1021/tx500526s. Epub 2015 Feb 16. Chem Res Toxicol. 2015. PMID: 25654186

7

Bioactivation of substituted thiophenes including α-chlorothiophene-containing compounds in human liver microsomes.

Chen W, Caceres-Cortes J, Zhang H, Zhang D, Humphreys WG, Gan J. Chen W, et al. Among authors: gan j. Chem Res Toxicol. 2011 May 16;24(5):663-9. doi: 10.1021/tx100386z. Epub 2011 Apr 13. Chem Res Toxicol. 2011. PMID: 21417487

8

Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans.

Chacko SA, Ly VT, Christopher LJ, Gan J. Chacko SA, et al. Among authors: gan j. Xenobiotica. 2020 Jun;50(6):621-629. doi: 10.1080/00498254.2019.1675100. Epub 2019 Oct 10. Xenobiotica. 2020. PMID: 31566996

9

In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin.

Gan J, Liu-Kreyche P, Humphreys WG. Gan J, et al. Cancer Chemother Pharmacol. 2012 Jan;69(1):51-6. doi: 10.1007/s00280-011-1672-2. Epub 2011 May 19. Cancer Chemother Pharmacol. 2012. PMID: 21594721

10

CYP3A4-mediated ester cleavage as the major metabolic pathway of the oral taxane 3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel (BMS-275183).

Zhang D, Ly VT, Lago M, Tian Y, Gan J, Humphreys WG, Cömezoglu SN. Zhang D, et al. Among authors: gan j. Drug Metab Dispos. 2009 Apr;37(4):710-8. doi: 10.1124/dmd.108.024398. Epub 2009 Jan 21. Drug Metab Dispos. 2009. PMID: 19158314

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,182 results

Search Page

Filters