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Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2beta) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: implications for prevention trials.
De Grijse J, Asanghanwa M, Nouthe B, Albrecher N, Goubert P, Vermeulen I, Van Der Meeren S, Decochez K, Weets I, Keymeulen B, Lampasona V, Wenzlau J, Hutton JC, Pipeleers D, Gorus FK; Belgian Diabetes Registry. De Grijse J, et al. Among authors: weets i. Diabetologia. 2010 Mar;53(3):517-24. doi: 10.1007/s00125-009-1618-y. Epub 2009 Nov 29. Diabetologia. 2010. PMID: 20091020
Male-to-female excess in diabetes diagnosed in early adulthood is not specific for the immune-mediated form nor is it HLA-DQ restricted: possible relation to increased body mass index.
Weets I, Van Autreve J, Van der Auwera BJ, Schuit FC, Du Caju MV, Decochez K, De Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Dorchy H, Quartier E, Gorus FK; Belgian Diabetes Registry. Weets I, et al. Diabetologia. 2001 Jan;44(1):40-7. doi: 10.1007/s001250051578. Diabetologia. 2001. PMID: 11206410
IA-2 autoantibodies predict impending type I diabetes in siblings of patients.
Decochez K, De Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Weets I, Vandemeulebroucke E, Truyen I, Kaufman L, Schuit FC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: weets i. Diabetologia. 2002 Dec;45(12):1658-66. doi: 10.1007/s00125-002-0949-8. Epub 2002 Nov 12. Diabetologia. 2002. PMID: 12488955
Seasonality in clinical onset of type 1 diabetes in belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence.
Weets I, Kaufman L, Van der Auwera B, Crenier L, Rooman RP, De Block C, Casteels K, Weber E, Coeckelberghs M, Laron Z, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Weets I, et al. Diabetologia. 2004 Apr;47(4):614-21. doi: 10.1007/s00125-004-1369-8. Diabetologia. 2004. PMID: 15298337
Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.
Decochez K, Truyen I, van der Auwera B, Weets I, Vandemeulebroucke E, de Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: weets i. Diabetologia. 2005 Apr;48(4):687-94. doi: 10.1007/s00125-005-1702-x. Epub 2005 Mar 9. Diabetologia. 2005. PMID: 15756536 Free article.
Identification of prediabetes in first-degree relatives at intermediate risk of type I diabetes.
Truyen I, De Grijse J, Weets I, Kaufman L, Pipeleers L, Nanos N, Decochez K, Hilbrands R, Kaufman JM, Keymeulen B, Mathieu C, Van Gaal L, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Truyen I, et al. Among authors: weets i. Clin Exp Immunol. 2007 Aug;149(2):243-50. doi: 10.1111/j.1365-2249.2007.03416.x. Epub 2007 May 22. Clin Exp Immunol. 2007. PMID: 17521324 Free PMC article.
Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives.
Truyen I, De Grijse J, Van Schravendijk C, De Smet D, Decochez K, Vandemeulebroucke E, Giri M, Keymeulen B, Mathieu C, Van Gaal L, De Pauw P, Weets I, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Truyen I, et al. Among authors: weets i. Diabetologia. 2007 Oct;50(10):2143-6. doi: 10.1007/s00125-007-0774-1. Epub 2007 Aug 9. Diabetologia. 2007. PMID: 17687539
Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
Vandemeulebroucke E, Gorus FK, Decochez K, Weets I, Keymeulen B, De Block C, Tits J, Pipeleers DG, Mathieu C; Belgian Diabetes Registry. Vandemeulebroucke E, et al. Among authors: weets i. Diabetes Metab. 2009 Sep;35(4):319-27. doi: 10.1016/j.diabet.2009.02.005. Epub 2009 Jul 31. Diabetes Metab. 2009. PMID: 19647467 Clinical Trial.
92 results