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Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.
Corti D, Langedijk JP, Hinz A, Seaman MS, Vanzetta F, Fernandez-Rodriguez BM, Silacci C, Pinna D, Jarrossay D, Balla-Jhagjhoorsingh S, Willems B, Zekveld MJ, Dreja H, O'Sullivan E, Pade C, Orkin C, Jeffs SA, Montefiori DC, Davis D, Weissenhorn W, McKnight A, Heeney JL, Sallusto F, Sattentau QJ, Weiss RA, Lanzavecchia A. Corti D, et al. Among authors: weissenhorn w. PLoS One. 2010 Jan 20;5(1):e8805. doi: 10.1371/journal.pone.0008805. PLoS One. 2010. PMID: 20098712 Free PMC article.
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Pinto D, Fenwick C, Caillat C, Silacci C, Guseva S, Dehez F, Chipot C, Barbieri S, Minola A, Jarrossay D, Tomaras GD, Shen X, Riva A, Tarkowski M, Schwartz O, Bruel T, Dufloo J, Seaman MS, Montefiori DC, Lanzavecchia A, Corti D, Pantaleo G, Weissenhorn W. Pinto D, et al. Among authors: weissenhorn w. Cell Host Microbe. 2019 Nov 13;26(5):623-637.e8. doi: 10.1016/j.chom.2019.09.016. Epub 2019 Oct 22. Cell Host Microbe. 2019. PMID: 31653484 Free PMC article.
Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
Sabin C, Corti D, Buzon V, Seaman MS, Lutje Hulsik D, Hinz A, Vanzetta F, Agatic G, Silacci C, Mainetti L, Scarlatti G, Sallusto F, Weiss R, Lanzavecchia A, Weissenhorn W. Sabin C, et al. Among authors: weissenhorn w. PLoS Pathog. 2010 Nov 18;6(11):e1001195. doi: 10.1371/journal.ppat.1001195. PLoS Pathog. 2010. PMID: 21124990 Free PMC article.
A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1.
Lai RP, Hock M, Radzimanowski J, Tonks P, Hulsik DL, Effantin G, Seilly DJ, Dreja H, Kliche A, Wagner R, Barnett SW, Tumba N, Morris L, LaBranche CC, Montefiori DC, Seaman MS, Heeney JL, Weissenhorn W. Lai RP, et al. Among authors: weissenhorn w. J Biol Chem. 2014 Oct 24;289(43):29912-26. doi: 10.1074/jbc.M114.569566. Epub 2014 Aug 26. J Biol Chem. 2014. PMID: 25160627 Free PMC article.
Characterization of a trimeric MPER containing HIV-1 gp41 antigen.
Hinz A, Schoehn G, Quendler H, Hulsik DL, Stiegler G, Katinger H, Seaman MS, Montefiori D, Weissenhorn W. Hinz A, et al. Among authors: weissenhorn w. Virology. 2009 Aug 1;390(2):221-7. doi: 10.1016/j.virol.2009.05.015. Epub 2009 Jun 18. Virology. 2009. PMID: 19539967 Free article.
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition.
Lutje Hulsik D, Liu YY, Strokappe NM, Battella S, El Khattabi M, McCoy LE, Sabin C, Hinz A, Hock M, Macheboeuf P, Bonvin AM, Langedijk JP, Davis D, Forsman Quigley A, Aasa-Chapman MM, Seaman MS, Ramos A, Poignard P, Favier A, Simorre JP, Weiss RA, Verrips CT, Weissenhorn W, Rutten L. Lutje Hulsik D, et al. Among authors: weissenhorn w. PLoS Pathog. 2013 Mar;9(3):e1003202. doi: 10.1371/journal.ppat.1003202. Epub 2013 Mar 7. PLoS Pathog. 2013. PMID: 23505368 Free PMC article.
Induction of Tier 1 HIV Neutralizing Antibodies by Envelope Trimers Incorporated into a Replication Competent Vesicular Stomatitis Virus Vector.
Bresk CA, Hofer T, Wilmschen S, Krismer M, Beierfuß A, Effantin G, Weissenhorn W, Hogan MJ, Jordan APO, Gelman RS, Montefiori DC, Liao HX, Schmitz JE, Haynes BF, von Laer D, Kimpel J. Bresk CA, et al. Among authors: weissenhorn w. Viruses. 2019 Feb 15;11(2):159. doi: 10.3390/v11020159. Viruses. 2019. PMID: 30769947 Free PMC article.
Virus membrane fusion.
Weissenhorn W, Hinz A, Gaudin Y. Weissenhorn W, et al. FEBS Lett. 2007 May 22;581(11):2150-5. doi: 10.1016/j.febslet.2007.01.093. Epub 2007 Feb 16. FEBS Lett. 2007. PMID: 17320081 Free PMC article. Review.
122 results