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A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine.
Verheul RJ, Hagenaars N, van Es T, van Gaal EV, de Jong PH, Bruijns S, Mastrobattista E, Slütter B, Que I, Heldens JG, van den Bosch H, Glansbeek HL, Hennink WE, Jiskoot W. Verheul RJ, et al. Among authors: hagenaars n. Eur J Pharm Sci. 2012 Mar 12;45(4):467-74. doi: 10.1016/j.ejps.2011.10.001. Epub 2011 Oct 8. Eur J Pharm Sci. 2012. PMID: 22009112
Rational design of nasal vaccines.
Slütter B, Hagenaars N, Jiskoot W. Slütter B, et al. Among authors: hagenaars n. J Drug Target. 2008 Jan;16(1):1-17. doi: 10.1080/10611860701637966. J Drug Target. 2008. PMID: 18172815 Review.
Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.
Slütter B, Bal S, Keijzer C, Mallants R, Hagenaars N, Que I, Kaijzel E, van Eden W, Augustijns P, Löwik C, Bouwstra J, Broere F, Jiskoot W. Slütter B, et al. Among authors: hagenaars n. Vaccine. 2010 Aug 31;28(38):6282-91. doi: 10.1016/j.vaccine.2010.06.121. Epub 2010 Jul 16. Vaccine. 2010. PMID: 20638455