Kaushal N - Search Results

1

A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice.

Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR. Xu YT, et al. Among authors: kaushal n. J Pharmacol Exp Ther. 2010 May;333(2):491-500. doi: 10.1124/jpet.109.161398. Epub 2010 Jan 25. J Pharmacol Exp Ther. 2010. PMID: 20100904 Free PMC article.

2

Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice.

Seminerio MJ, Kaushal N, Shaikh J, Huber JD, Coop A, Matsumoto RR. Seminerio MJ, et al. Among authors: kaushal n. Pharmacol Biochem Behav. 2011 Mar;98(1):12-20. doi: 10.1016/j.pbb.2010.11.023. Epub 2010 Dec 2. Pharmacol Biochem Behav. 2011. PMID: 21130800 Free PMC article.

3

Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents.

Kaushal N, Robson MJ, Vinnakota H, Narayanan S, Avery BA, McCurdy CR, Matsumoto RR. Kaushal N, et al. AAPS J. 2011 Sep;13(3):336-46. doi: 10.1208/s12248-011-9274-9. Epub 2011 Apr 15. AAPS J. 2011. PMID: 21494909 Free PMC article.

4

CM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in mice.

Kaushal N, Seminerio MJ, Shaikh J, Medina MA, Mesangeau C, Wilson LL, McCurdy CR, Matsumoto RR. Kaushal N, et al. Neuropharmacology. 2011 Oct-Nov;61(5-6):992-1000. doi: 10.1016/j.neuropharm.2011.06.028. Epub 2011 Jul 7. Neuropharmacology. 2011. PMID: 21762711 Free PMC article.

5

Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.

Kaushal N, Seminerio MJ, Robson MJ, McCurdy CR, Matsumoto RR. Kaushal N, et al. Eur Neuropsychopharmacol. 2013 Aug;23(8):960-71. doi: 10.1016/j.euroneuro.2012.08.005. Epub 2012 Aug 24. Eur Neuropsychopharmacol. 2013. PMID: 22921523 Free PMC article.

6

The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice.

Seminerio MJ, Hansen R, Kaushal N, Zhang HT, McCurdy CR, Matsumoto RR. Seminerio MJ, et al. Among authors: kaushal n. Int J Neuropsychopharmacol. 2013 Jun;16(5):1033-44. doi: 10.1017/S1461145712000831. Epub 2012 Aug 29. Int J Neuropsychopharmacol. 2013. PMID: 22932447 Free article.

7

Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro.

Kaushal N, Robson MJ, Rosen A, McCurdy CR, Matsumoto RR. Kaushal N, et al. Eur J Pharmacol. 2014 Feb 5;724:193-203. doi: 10.1016/j.ejphar.2013.12.039. Epub 2013 Dec 28. Eur J Pharmacol. 2014. PMID: 24380829 Free PMC article.

8

Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.

Mésangeau C, Narayanan S, Green AM, Shaikh J, Kaushal N, Viard E, Xu YT, Fishback JA, Poupaert JH, Matsumoto RR, McCurdy CR. Mésangeau C, et al. Among authors: kaushal n. J Med Chem. 2008 Mar 13;51(5):1482-6. doi: 10.1021/jm701357m. Epub 2008 Feb 16. J Med Chem. 2008. PMID: 18278854

9

Role of sigma receptors in methamphetamine-induced neurotoxicity.

Kaushal N, Matsumoto RR. Kaushal N, et al. Curr Neuropharmacol. 2011 Mar;9(1):54-7. doi: 10.2174/157015911795016930. Curr Neuropharmacol. 2011. PMID: 21886562 Free PMC article.

10

AC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells.

Kaushal N, Elliott M, Robson MJ, Iyer AK, Rojanasakul Y, Coop A, Matsumoto RR. Kaushal N, et al. Mol Pharmacol. 2012 Mar;81(3):299-308. doi: 10.1124/mol.111.074120. Epub 2011 Nov 18. Mol Pharmacol. 2012. PMID: 22101517 Free PMC article.

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