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24 results

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Page 1
Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system.
Gattinoni S, De Simone C, Dallavalle S, Fezza F, Nannei R, Amadio D, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M. Gattinoni S, et al. Among authors: minetti p. ChemMedChem. 2010 Mar 1;5(3):357-60. doi: 10.1002/cmdc.200900472. ChemMedChem. 2010. PMID: 20112328 No abstract available.
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.
Butini S, Gemma S, Brindisi M, Maramai S, Minetti P, Celona D, Napolitano R, Borsini F, Cabri W, Fezza F, Merlini L, Dallavalle S, Campiani G, Maccarrone M. Butini S, et al. Among authors: minetti p. Bioorg Med Chem Lett. 2013 Jan 15;23(2):492-5. doi: 10.1016/j.bmcl.2012.11.035. Epub 2012 Nov 22. Bioorg Med Chem Lett. 2013. PMID: 23237837 Free article.
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Gattinoni S, Simone CD, Dallavalle S, Fezza F, Nannei R, Battista N, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M. Gattinoni S, et al. Among authors: minetti p. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4406-11. doi: 10.1016/j.bmcl.2010.06.050. Epub 2010 Jun 15. Bioorg Med Chem Lett. 2010. PMID: 20591666
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
Butini S, Brindisi M, Gemma S, Minetti P, Cabri W, Gallo G, Vincenti S, Talamonti E, Borsini F, Caprioli A, Stasi MA, Di Serio S, Ros S, Borrelli G, Maramai S, Fezza F, Campiani G, Maccarrone M. Butini S, et al. Among authors: minetti p. J Med Chem. 2012 Aug 9;55(15):6898-915. doi: 10.1021/jm300689c. Epub 2012 Jul 26. J Med Chem. 2012. PMID: 22779702
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
Grillo A, Fezza F, Chemi G, Colangeli R, Brogi S, Fazio D, Federico S, Papa A, Relitti N, Di Maio R, Giorgi G, Lamponi S, Valoti M, Gorelli B, Saponara S, Benedusi M, Pecorelli A, Minetti P, Valacchi G, Butini S, Campiani G, Gemma S, Maccarrone M, Di Giovanni G. Grillo A, et al. Among authors: minetti p. ACS Chem Neurosci. 2021 May 5;12(9):1716-1736. doi: 10.1021/acschemneuro.1c00192. Epub 2021 Apr 23. ACS Chem Neurosci. 2021. PMID: 33890763
Synthesis and biological evaluation of metabolites of 2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), a potent antagonist of the A2A adenosine receptor for the treatment of Parkinson's disease.
Piersanti G, Bartoccini F, Lucarini S, Cabri W, Stasi MA, Riccioni T, Borsini F, Tarzia G, Minetti P. Piersanti G, et al. Among authors: minetti p. J Med Chem. 2013 Jul 11;56(13):5456-63. doi: 10.1021/jm400491x. Epub 2013 Jun 24. J Med Chem. 2013. PMID: 23789814
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain.
Brindisi M, Borrelli G, Brogi S, Grillo A, Maramai S, Paolino M, Benedusi M, Pecorelli A, Valacchi G, Di Cesare Mannelli L, Ghelardini C, Allarà M, Ligresti A, Minetti P, Campiani G, di Marzo V, Butini S, Gemma S. Brindisi M, et al. Among authors: minetti p. ChemMedChem. 2018 Oct 8;13(19):2090-2103. doi: 10.1002/cmdc.201800397. Epub 2018 Aug 30. ChemMedChem. 2018. PMID: 30085402
24 results