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Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.
Nesburn AB, Bettahi I, Dasgupta G, Chentoufi AA, Zhang X, You S, Morishige N, Wahlert AJ, Brown DJ, Jester JV, Wechsler SL, BenMohamed L. Nesburn AB, et al. Among authors: dasgupta g. J Virol. 2007 Jul;81(14):7647-61. doi: 10.1128/JVI.00294-07. Epub 2007 May 2. J Virol. 2007. PMID: 17475646 Free PMC article.
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.
Chentoufi AA, Dasgupta G, Nesburn AB, Bettahi I, Binder NR, Choudhury ZS, Chamberlain WD, Wechsler SL, BenMohamed L. Chentoufi AA, et al. Among authors: dasgupta g. Clin Vaccine Immunol. 2010 Mar;17(3):342-53. doi: 10.1128/CVI.00347-09. Epub 2010 Jan 20. Clin Vaccine Immunol. 2010. PMID: 20089796 Free PMC article.
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn AB, BenMohamed L. Dasgupta G, et al. Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3321-33. doi: 10.1167/iovs.10-6522. Invest Ophthalmol Vis Sci. 2011. PMID: 21273544 Free PMC article.
The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism.
Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn AB, Wechsler SL, BenMohamed L. Chentoufi AA, et al. Among authors: dasgupta g. J Virol. 2011 Sep;85(17):9127-38. doi: 10.1128/JVI.00587-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715478 Free PMC article.
59 results