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452 results

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Page 1
Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.
Therrien E, Larouche G, Nguyen N, Rahil J, Lemieux AM, Li Z, Fournel M, Yan TP, Landry AJ, Lefebvre S, Wang JJ, MacBeth K, Heise C, Nguyen A, Besterman JM, Déziel R, Wahhab A. Therrien E, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2514-8. doi: 10.1016/j.bmcl.2015.04.068. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25971769
Phase I Study of CC-486 Alone and in Combination with Carboplatin or nab-Paclitaxel in Patients with Relapsed or Refractory Solid Tumors.
Von Hoff DD, Rasco DW, Heath EI, Munster PN, Schellens JHM, Isambert N, Le Tourneau C, O'Neil B, Mathijssen RHJ, Lopez-Martin JA, Edenfield WJ, Martin M, LoRusso PM, Bray GL, DiMartino J, Nguyen A, Liu K, Laille E, Bendell JC. Von Hoff DD, et al. Clin Cancer Res. 2018 Sep 1;24(17):4072-4080. doi: 10.1158/1078-0432.CCR-17-3716. Epub 2018 May 15. Clin Cancer Res. 2018. PMID: 29764853 Free PMC article. Clinical Trial.
2024 Update of the RECOVER-Adult Long COVID Research Index.
Geng LN, Erlandson KM, Hornig M, Letts R, Selvaggi C, Ashktorab H, Atieh O, Bartram L, Brim H, Brosnahan SB, Brown J, Castro M, Charney A, Chen P, Deeks SG, Erdmann N, Flaherman VJ, Ghamloush MA, Goepfert P, Goldman JD, Han JE, Hess R, Hirshberg E, Hoover SE, Katz SD, Kelly JD, Klein JD, Krishnan JA, Lee-Iannotti J, Levitan EB, Marconi VC, Metz TD, Modes ME, Nikolich JŽ, Novak RM, Ofotokun I, Okumura MJ, Parthasarathy S, Patterson TF, Peluso MJ, Poppas A, Quintero Cardona O, Scott J, Shellito J, Sherif ZA, Singer NG, Taylor BS, Thaweethai T, Verduzco-Gutierrez M, Wisnivesky J, McComsey GA, Horwitz LI, Foulkes AS; RECOVER Consortium. Geng LN, et al. JAMA. 2024 Dec 18. doi: 10.1001/jama.2024.24184. Online ahead of print. JAMA. 2024. PMID: 39693079
A combined AI and cell biology approach surfaces targets and mechanistically distinct Inflammasome inhibitors.
Chen D, Plott T, Wiest M, Van Trump W, Komalo B, Nguyen D, Marsh C, Heinrich J, Fuller CJ, Nicolaisen L, Cambronero E, Nguyen A, Elabd C, Rubbo F, DeVay Jacobson R. Chen D, et al. Among authors: nguyen a. iScience. 2024 Nov 16;27(12):111404. doi: 10.1016/j.isci.2024.111404. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687021 Free PMC article.
A randomized trial comparing safety, immunogenicity and efficacy of self-amplifying mRNA and adenovirus-vector COVID-19 vaccines.
Ho NT, Hughes SG, Sekulovich R, Ta VT, Nguyen TV, Van Pham AT, Luong QC, Le Tran LT, Van Luu AT, Nguyen AN, Pham HT, Nguyen VT, Berdieva D, Bugarini R, Liu X, Verhoeven C, Smolenov I, Nguyen XH. Ho NT, et al. Among authors: nguyen an. NPJ Vaccines. 2024 Nov 23;9(1):233. doi: 10.1038/s41541-024-01017-5. NPJ Vaccines. 2024. PMID: 39580505 Free PMC article.
452 results