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305 results

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Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study.
Lilly MB, Ottmann OG, Shah NP, Larson RA, Reiffers JJ, Ehninger G, Müller MC, Charbonnier A, Bullorsky E, Dombret H, Brigid Bradley-Garelik M, Zhu C, Martinelli G. Lilly MB, et al. Among authors: ottmann og. Am J Hematol. 2010 Mar;85(3):164-70. doi: 10.1002/ajh.21615. Am J Hematol. 2010. PMID: 20131302 Free article. Clinical Trial.
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.
Sawyers CL, Hochhaus A, Feldman E, Goldman JM, Miller CB, Ottmann OG, Schiffer CA, Talpaz M, Guilhot F, Deininger MW, Fischer T, O'Brien SG, Stone RM, Gambacorti-Passerini CB, Russell NH, Reiffers JJ, Shea TC, Chapuis B, Coutre S, Tura S, Morra E, Larson RA, Saven A, Peschel C, Gratwohl A, Mandelli F, Ben-Am M, Gathmann I, Capdeville R, Paquette RL, Druker BJ. Sawyers CL, et al. Among authors: ottmann og. Blood. 2002 May 15;99(10):3530-9. doi: 10.1182/blood.v99.10.3530. Blood. 2002. PMID: 11986204 Free article. Clinical Trial.
Acute lymphoblastic leukemia.
Hoelzer D, Gökbuget N, Ottmann O, Pui CH, Relling MV, Appelbaum FR, van Dongen JJ, Szczepański T. Hoelzer D, et al. Hematology Am Soc Hematol Educ Program. 2002:162-92. doi: 10.1182/asheducation-2002.1.162. Hematology Am Soc Hematol Educ Program. 2002. PMID: 12446423 Review.
Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon alpha/ara-C.
Müller MC, Gattermann N, Lahaye T, Deininger MW, Berndt A, Fruehauf S, Neubauer A, Fischer T, Hossfeld DK, Schneller F, Krause SW, Nerl C, Sayer HG, Ottmann OG, Waller C, Aulitzky W, le Coutre P, Freund M, Merx K, Paschka P, König H, Kreil S, Berger U, Gschaidmeier H, Hehlmann R, Hochhaus A. Müller MC, et al. Among authors: ottmann og. Leukemia. 2003 Dec;17(12):2392-400. doi: 10.1038/sj.leu.2403157. Leukemia. 2003. PMID: 14523462 Clinical Trial.
Early prediction of response in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) treated with imatinib.
Wassmann B, Pfeifer H, Scheuring UJ, Binckebanck A, Gökbuget N, Atta J, Brück P, Rieder H, Schoch C, Leimer L, Schwerdtfeger R, Ehninger G, Lipp T, Perz J, Stelljes M, Gschaidmeier H, Hoelzer D, Ottmann OG. Wassmann B, et al. Among authors: ottmann og. Blood. 2004 Feb 15;103(4):1495-8. doi: 10.1182/blood-2003-01-0154. Epub 2003 Oct 23. Blood. 2004. PMID: 14576058 Free article. Clinical Trial.
Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588.
le Coutre P, Kreuzer KA, Pursche S, Bonin Mv, Leopold T, Baskaynak G, Dörken B, Ehninger G, Ottmann O, Jenke A, Bornhäuser M, Schleyer E. le Coutre P, et al. Cancer Chemother Pharmacol. 2004 Apr;53(4):313-23. doi: 10.1007/s00280-003-0741-6. Epub 2003 Dec 5. Cancer Chemother Pharmacol. 2004. PMID: 14658008
Imatinib mesylate selectively influences the cellular metabolism of cytarabine in BCR/ABL negative leukemia cell lines and normal CD34+ progenitor cells.
Bornhäuser M, Illmer T, Le Coutre P, Pursche J, von Bonin M, Freiberg-Richter J, Schaich M, Platzbecker U, Thiede C, Ottmann OG, Köhne Ch, Braess J, Ehninger G, Schleyer E. Bornhäuser M, et al. Among authors: ottmann og. Ann Hematol. 2004;83 Suppl 1:S61-4. doi: 10.1007/s00277-004-0850-2. Ann Hematol. 2004. PMID: 15124675 Review.
Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis.
Cortes J, Rousselot P, Kim DW, Ritchie E, Hamerschlak N, Coutre S, Hochhaus A, Guilhot F, Saglio G, Apperley J, Ottmann O, Shah N, Erben P, Branford S, Agarwal P, Gollerkeri A, Baccarani M. Cortes J, et al. Blood. 2007 Apr 15;109(8):3207-13. doi: 10.1182/blood-2006-09-046888. Epub 2006 Dec 21. Blood. 2007. PMID: 17185463 Free article. Clinical Trial.
305 results