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Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse.
Rosenquist TA, Einolf HJ, Dickman KG, Wang L, Smith A, Grollman AP. Rosenquist TA, et al. Among authors: dickman kg. Drug Metab Dispos. 2010 May;38(5):761-8. doi: 10.1124/dmd.110.032201. Epub 2010 Feb 17. Drug Metab Dispos. 2010. PMID: 20164109 Free PMC article.
Bioactivation of the human carcinogen aristolochic acid.
Sidorenko VS, Attaluri S, Zaitseva I, Iden CR, Dickman KG, Johnson F, Grollman AP. Sidorenko VS, et al. Among authors: dickman kg. Carcinogenesis. 2014 Aug;35(8):1814-22. doi: 10.1093/carcin/bgu095. Epub 2014 Apr 17. Carcinogenesis. 2014. PMID: 24743514 Free PMC article.
Aristolochic Acid in the Etiology of Renal Cell Carcinoma.
Hoang ML, Chen CH, Chen PC, Roberts NJ, Dickman KG, Yun BH, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA. Hoang ML, et al. Among authors: dickman kg. Cancer Epidemiol Biomarkers Prev. 2016 Dec;25(12):1600-1608. doi: 10.1158/1055-9965.EPI-16-0219. Epub 2016 Aug 23. Cancer Epidemiol Biomarkers Prev. 2016. PMID: 27555084 Free PMC article.
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.
Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL. Chang SY, et al. Among authors: dickman kg. JCI Insight. 2017 Nov 16;2(22):e95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202460 Free PMC article.
Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.
Castells X, Karanović S, Ardin M, Tomić K, Xylinas E, Durand G, Villar S, Forey N, Le Calvez-Kelm F, Voegele C, Karlović K, Mišić M, Dittrich D, Dolgalev I, McKay J, Shariat SF, Sidorenko VS, Fernandes A, Heguy A, Dickman KG, Olivier M, Grollman AP, Jelaković B, Zavadil J. Castells X, et al. Among authors: dickman kg. Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1873-81. doi: 10.1158/1055-9965.EPI-15-0553. Epub 2015 Sep 17. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 26383547 Free PMC article.
54 results