Petermann E - Search Results

1

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

Petermann E, Orta ML, Issaeva N, Schultz N, Helleday T. Petermann E, et al. Mol Cell. 2010 Feb 26;37(4):492-502. doi: 10.1016/j.molcel.2010.01.021. Mol Cell. 2010. PMID: 20188668 Free PMC article.

2

DNA replication-associated lesions: importance in early tumorigenesis and cancer therapy.

Petermann E, Helleday T. Petermann E, et al. Biochem Soc Trans. 2007 Nov;35(Pt 5):1352-4. doi: 10.1042/BST0351352. Biochem Soc Trans. 2007. PMID: 17956349 Review.

3

Claspin promotes normal replication fork rates in human cells.

Petermann E, Helleday T, Caldecott KW. Petermann E, et al. Mol Biol Cell. 2008 Jun;19(6):2373-8. doi: 10.1091/mbc.e07-10-1035. Epub 2008 Mar 19. Mol Biol Cell. 2008. PMID: 18353973 Free PMC article.

4

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

Bryant HE, Petermann E, Schultz N, Jemth AS, Loseva O, Issaeva N, Johansson F, Fernandez S, McGlynn P, Helleday T. Bryant HE, et al. Among authors: petermann e. EMBO J. 2009 Sep 2;28(17):2601-15. doi: 10.1038/emboj.2009.206. Epub 2009 Jul 23. EMBO J. 2009. PMID: 19629035 Free PMC article.

5

Chk1 promotes replication fork progression by controlling replication initiation.

Petermann E, Woodcock M, Helleday T. Petermann E, et al. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16090-5. doi: 10.1073/pnas.1005031107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805465 Free PMC article.

6

Pathways of mammalian replication fork restart.

Petermann E, Helleday T. Petermann E, et al. Nat Rev Mol Cell Biol. 2010 Oct;11(10):683-7. doi: 10.1038/nrm2974. Epub 2010 Sep 15. Nat Rev Mol Cell Biol. 2010. PMID: 20842177 Review.

7

Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control.

Wilsker D, Petermann E, Helleday T, Bunz F. Wilsker D, et al. Among authors: petermann e. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20752-7. doi: 10.1073/pnas.0806917106. Epub 2008 Dec 17. Proc Natl Acad Sci U S A. 2008. PMID: 19091954 Free PMC article.

8

Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

Groth P, Ausländer S, Majumder MM, Schultz N, Johansson F, Petermann E, Helleday T. Groth P, et al. Among authors: petermann e. J Mol Biol. 2010 Sep 10;402(1):70-82. doi: 10.1016/j.jmb.2010.07.010. Epub 2010 Jul 17. J Mol Biol. 2010. PMID: 20643142

9

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.

Bolderson E, Petermann E, Croft L, Suraweera A, Pandita RK, Pandita TK, Helleday T, Khanna KK, Richard DJ. Bolderson E, et al. Among authors: petermann e. Nucleic Acids Res. 2014 Jun;42(10):6326-36. doi: 10.1093/nar/gku276. Epub 2014 Apr 20. Nucleic Acids Res. 2014. PMID: 24753408 Free PMC article.

10

DNA repair pathways as targets for cancer therapy.

Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. Helleday T, et al. Among authors: petermann e. Nat Rev Cancer. 2008 Mar;8(3):193-204. doi: 10.1038/nrc2342. Nat Rev Cancer. 2008. PMID: 18256616 Review.

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