de Koning HP - Search Results

1

Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.

Berg M, Kohl L, Van der Veken P, Joossens J, Al-Salabi MI, Castagna V, Giannese F, Cos P, Versées W, Steyaert J, Grellier P, Haemers A, Degano M, Maes L, de Koning HP, Augustyns K. Berg M, et al. Among authors: de koning hp. Antimicrob Agents Chemother. 2010 May;54(5):1900-8. doi: 10.1128/AAC.01787-09. Epub 2010 Mar 1. Antimicrob Agents Chemother. 2010. PMID: 20194690 Free PMC article.

2

A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter.

Al-Salabi MI, Wallace LJ, De Koning HP. Al-Salabi MI, et al. Among authors: de koning hp. Mol Pharmacol. 2003 Apr;63(4):814-20. doi: 10.1124/mol.63.4.814. Mol Pharmacol. 2003. PMID: 12644582

3

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

Burchmore RJ, Wallace LJ, Candlish D, Al-Salabi MI, Beal PR, Barrett MP, Baldwin SA, de Koning HP. Burchmore RJ, et al. Among authors: de koning hp. J Biol Chem. 2003 Jun 27;278(26):23502-7. doi: 10.1074/jbc.M301252200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707261 Free article.

4

Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

De Koning HP, Al-Salabi MI, Cohen AM, Coombs GH, Wastling JM. De Koning HP, et al. Int J Parasitol. 2003 Jul 30;33(8):821-31. doi: 10.1016/s0020-7519(03)00091-2. Int J Parasitol. 2003. PMID: 12865082

5

The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

de Koning HP, Anderson LF, Stewart M, Burchmore RJ, Wallace LJ, Barrett MP. de Koning HP, et al. Antimicrob Agents Chemother. 2004 May;48(5):1515-9. doi: 10.1128/AAC.48.5.1515-1519.2004. Antimicrob Agents Chemother. 2004. PMID: 15105099 Free PMC article.

6

Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance.

Natto MJ, Wallace LJ, Candlish D, Al-Salabi MI, Coutts SE, de Koning HP. Natto MJ, et al. Among authors: de koning hp. Exp Parasitol. 2005 Feb;109(2):80-6. doi: 10.1016/j.exppara.2004.11.004. Epub 2005 Jan 8. Exp Parasitol. 2005. PMID: 15687014

7

Identification of the first pyrimidine nucleobase transporter in Leishmania: similarities with the Trypanosoma brucei U1 transporter and antileishmanial activity of uracil analogues.

Papageorgiou IG, Yakob L, Al Salabi MI, Diallinas G, Soteriadou KP, De Koning HP. Papageorgiou IG, et al. Among authors: de koning hp. Parasitology. 2005 Mar;130(Pt 3):275-83. doi: 10.1017/s0031182004006626. Parasitology. 2005. PMID: 15796010

8

Purine nucleobase transport in amastigotes of Leishmania mexicana: involvement in allopurinol uptake.

Al-Salabi MI, de Koning HP. Al-Salabi MI, et al. Among authors: de koning hp. Antimicrob Agents Chemother. 2005 Sep;49(9):3682-9. doi: 10.1128/AAC.49.9.3682-3689.2005. Antimicrob Agents Chemother. 2005. PMID: 16127040 Free PMC article.

9

Trypanosoma brucei: a survey of pyrimidine transport activities.

Gudin S, Quashie NB, Candlish D, Al-Salabi MI, Jarvis SM, Ranford-Cartwright LC, de Koning HP. Gudin S, et al. Among authors: de koning hp. Exp Parasitol. 2006 Oct;114(2):118-25. doi: 10.1016/j.exppara.2006.02.018. Epub 2006 Apr 18. Exp Parasitol. 2006. PMID: 16620810

10

Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

Al-Salabi MI, Wallace LJ, Lüscher A, Mäser P, Candlish D, Rodenko B, Gould MK, Jabeen I, Ajith SN, de Koning HP. Al-Salabi MI, et al. Among authors: de koning hp. Mol Pharmacol. 2007 Mar;71(3):921-9. doi: 10.1124/mol.106.031559. Epub 2006 Dec 21. Mol Pharmacol. 2007. PMID: 17185380

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