Scheel TK - Search Results

1

Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies.

Gottwein JM, Scheel TK, Callendret B, Li YP, Eccleston HB, Engle RE, Govindarajan S, Satterfield W, Purcell RH, Walker CM, Bukh J. Gottwein JM, et al. Among authors: scheel tk. J Virol. 2010 May;84(10):5277-93. doi: 10.1128/JVI.02667-09. Epub 2010 Mar 3. J Virol. 2010. PMID: 20200247 Free PMC article.

2

Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses.

Gottwein JM, Scheel TK, Hoegh AM, Lademann JB, Eugen-Olsen J, Lisby G, Bukh J. Gottwein JM, et al. Among authors: scheel tk. Gastroenterology. 2007 Nov;133(5):1614-26. doi: 10.1053/j.gastro.2007.08.005. Epub 2007 Aug 3. Gastroenterology. 2007. PMID: 17983807

3

Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization.

Scheel TK, Gottwein JM, Jensen TB, Prentoe JC, Hoegh AM, Alter HJ, Eugen-Olsen J, Bukh J. Scheel TK, et al. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):997-1002. doi: 10.1073/pnas.0711044105. Epub 2008 Jan 14. Proc Natl Acad Sci U S A. 2008. PMID: 18195353 Free PMC article.

4

Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection.

Jensen TB, Gottwein JM, Scheel TK, Hoegh AM, Eugen-Olsen J, Bukh J. Jensen TB, et al. Among authors: scheel tk. J Infect Dis. 2008 Dec 15;198(12):1756-65. doi: 10.1086/593021. J Infect Dis. 2008. PMID: 19032070

5

Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs.

Gottwein JM, Scheel TK, Jensen TB, Lademann JB, Prentoe JC, Knudsen ML, Hoegh AM, Bukh J. Gottwein JM, et al. Among authors: scheel tk. Hepatology. 2009 Feb;49(2):364-77. doi: 10.1002/hep.22673. Hepatology. 2009. PMID: 19148942

6

Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-α.

Scheel TK, Gottwein JM, Mikkelsen LS, Jensen TB, Bukh J. Scheel TK, et al. Gastroenterology. 2011 Mar;140(3):1032-42. doi: 10.1053/j.gastro.2010.11.036. Epub 2010 Nov 25. Gastroenterology. 2011. PMID: 21111742

7

Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization.

Prentoe J, Jensen TB, Meuleman P, Serre SB, Scheel TK, Leroux-Roels G, Gottwein JM, Bukh J. Prentoe J, et al. Among authors: scheel tk. J Virol. 2011 Mar;85(5):2224-34. doi: 10.1128/JVI.01594-10. Epub 2010 Dec 1. J Virol. 2011. PMID: 21123377 Free PMC article.

8

Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations.

Scheel TK, Gottwein JM, Carlsen TH, Li YP, Jensen TB, Spengler U, Weis N, Bukh J. Scheel TK, et al. J Virol. 2011 Mar;85(6):2891-906. doi: 10.1128/JVI.01605-10. Epub 2010 Dec 22. J Virol. 2011. PMID: 21177811 Free PMC article.

9

Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A.

Gottwein JM, Jensen TB, Mathiesen CK, Meuleman P, Serre SB, Lademann JB, Ghanem L, Scheel TK, Leroux-Roels G, Bukh J. Gottwein JM, et al. Among authors: scheel tk. J Virol. 2011 Sep;85(17):8913-28. doi: 10.1128/JVI.00049-11. Epub 2011 Jun 22. J Virol. 2011. PMID: 21697486 Free PMC article.

10

Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses.

Gottwein JM, Scheel TK, Jensen TB, Ghanem L, Bukh J. Gottwein JM, et al. Among authors: scheel tk. Gastroenterology. 2011 Sep;141(3):1067-79. doi: 10.1053/j.gastro.2011.06.004. Epub 2011 Jun 12. Gastroenterology. 2011. PMID: 21699793

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