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Page 1
A genome-wide association study of alcohol dependence.
Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium. Bierut LJ, et al. Among authors: wang jc. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2. Proc Natl Acad Sci U S A. 2010. PMID: 20202923 Free PMC article.
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI Jr, Tischfield J, Porjesz B, Edenberg HJ, Hesselbrock V, Crowe R, Schuckit M, Begleiter H, Reich T, Goate AM, Bierut LJ. Wang JC, et al. Hum Mol Genet. 2004 Sep 1;13(17):1903-11. doi: 10.1093/hmg/ddh194. Epub 2004 Jun 30. Hum Mol Genet. 2004. PMID: 15229186
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM. Hinrichs AL, et al. Among authors: wang jc. Am J Hum Genet. 2006 Jan;78(1):103-11. doi: 10.1086/499253. Epub 2005 Nov 21. Am J Hum Genet. 2006. PMID: 16385453 Free PMC article.
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, Ballinger DG, Rice JP, Bierut LJ. Saccone SF, et al. Among authors: wang jc. Hum Mol Genet. 2007 Jan 1;16(1):36-49. doi: 10.1093/hmg/ddl438. Epub 2006 Nov 29. Hum Mol Genet. 2007. PMID: 17135278 Free PMC article.
Novel genes identified in a high-density genome wide association study for nicotine dependence.
Bierut LJ, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF, Swan GE, Rutter J, Bertelsen S, Fox L, Fugman D, Goate AM, Hinrichs AL, Konvicka K, Martin NG, Montgomery GW, Saccone NL, Saccone SF, Wang JC, Chase GA, Rice JP, Ballinger DG. Bierut LJ, et al. Among authors: wang jc. Hum Mol Genet. 2007 Jan 1;16(1):24-35. doi: 10.1093/hmg/ddl441. Epub 2006 Dec 7. Hum Mol Genet. 2007. PMID: 17158188 Free PMC article.
Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk.
Dick DM, Agrawal A, Wang JC, Hinrichs A, Bertelsen S, Bucholz KK, Schuckit M, Kramer J, Nurnberger J Jr, Tischfield J, Edenberg HJ, Goate A, Bierut LJ. Dick DM, et al. Among authors: wang jc. Addiction. 2007 Jul;102(7):1131-9. doi: 10.1111/j.1360-0443.2007.01871.x. Addiction. 2007. PMID: 17567401
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J Jr, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A. Dick DM, et al. Among authors: wang jc. Alcohol Clin Exp Res. 2007 Oct;31(10):1645-53. doi: 10.1111/j.1530-0277.2007.00470.x. Alcohol Clin Exp Res. 2007. PMID: 17850642
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Agrawal A, Hinrichs AL, Dunn G, Bertelsen S, Dick DM, Saccone SF, Saccone NL, Grucza RA, Wang JC, Cloninger CR, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Bucholz KK, Kuperman S, Nurnberger JI Jr, Porjesz B, Schuckit MA, Goate AM, Bierut LJ. Agrawal A, et al. Among authors: wang jc. Drug Alcohol Depend. 2008 Jan 11;93(1-2):12-20. doi: 10.1016/j.drugalcdep.2007.08.015. Epub 2007 Oct 17. Drug Alcohol Depend. 2008. PMID: 17942244 Free PMC article.
A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9.
Dick DM, Aliev F, Wang JC, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger J Jr, Xuei X, Conneally PM, Schuckit M, Almasy L, Crowe R, Kuperman S, Kramer J, Tischfield JA, Hesselbrock V, Edenberg HJ, Porjesz B, Rice JP, Bierut L, Goate A. Dick DM, et al. Among authors: wang jc. Biol Psychiatry. 2008 Jun 1;63(11):1047-53. doi: 10.1016/j.biopsych.2007.11.005. Epub 2007 Dec 27. Biol Psychiatry. 2008. PMID: 18163977 Free PMC article.
3,055 results