Sacharidou A - Search Results

1

Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events.

Sacharidou A, Koh W, Stratman AN, Mayo AM, Fisher KE, Davis GE. Sacharidou A, et al. Blood. 2010 Jun 24;115(25):5259-69. doi: 10.1182/blood-2009-11-252692. Epub 2010 Mar 9. Blood. 2010. PMID: 20215637 Free PMC article.

2

In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis.

Koh W, Stratman AN, Sacharidou A, Davis GE. Koh W, et al. Among authors: sacharidou a. Methods Enzymol. 2008;443:83-101. doi: 10.1016/S0076-6879(08)02005-3. Methods Enzymol. 2008. PMID: 18772012

3

Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices.

Stratman AN, Saunders WB, Sacharidou A, Koh W, Fisher KE, Zawieja DC, Davis MJ, Davis GE. Stratman AN, et al. Among authors: sacharidou a. Blood. 2009 Jul 9;114(2):237-47. doi: 10.1182/blood-2008-12-196451. Epub 2009 Apr 1. Blood. 2009. PMID: 19339693 Free PMC article.

4

Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation.

Koh W, Sachidanandam K, Stratman AN, Sacharidou A, Mayo AM, Murphy EA, Cheresh DA, Davis GE. Koh W, et al. Among authors: sacharidou a. J Cell Sci. 2009 Jun 1;122(Pt 11):1812-22. doi: 10.1242/jcs.045799. Epub 2009 May 12. J Cell Sci. 2009. PMID: 19435802 Free PMC article.

5

MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices.

Fisher KE, Sacharidou A, Stratman AN, Mayo AM, Fisher SB, Mahan RD, Davis MJ, Davis GE. Fisher KE, et al. Among authors: sacharidou a. J Cell Sci. 2009 Dec 15;122(Pt 24):4558-69. doi: 10.1242/jcs.050724. Epub 2009 Nov 24. J Cell Sci. 2009. PMID: 19934222 Free PMC article.

6

Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling.

Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O. Xu K, et al. Among authors: sacharidou a. Dev Cell. 2011 Apr 19;20(4):526-39. doi: 10.1016/j.devcel.2011.02.010. Epub 2011 Mar 10. Dev Cell. 2011. PMID: 21396893 Free PMC article.

7

Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting.

Davis GE, Stratman AN, Sacharidou A, Koh W. Davis GE, et al. Among authors: sacharidou a. Int Rev Cell Mol Biol. 2011;288:101-65. doi: 10.1016/B978-0-12-386041-5.00003-0. Int Rev Cell Mol Biol. 2011. PMID: 21482411 Free PMC article. Review.

8

Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.

Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY. Chan AC, et al. Among authors: sacharidou a. J Clin Invest. 2011 May;121(5):1871-81. doi: 10.1172/JCI44393. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490399 Free PMC article.

9

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG.

Yuan L, Sacharidou A, Stratman AN, Le Bras A, Zwiers PJ, Spokes K, Bhasin M, Shih SC, Nagy JA, Molema G, Aird WC, Davis GE, Oettgen P. Yuan L, et al. Among authors: sacharidou a. Blood. 2011 Jul 28;118(4):1145-53. doi: 10.1182/blood-2010-10-315275. Epub 2011 May 31. Blood. 2011. PMID: 21628409 Free PMC article.

10

Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices.

Sacharidou A, Stratman AN, Davis GE. Sacharidou A, et al. Cells Tissues Organs. 2012;195(1-2):122-43. doi: 10.1159/000331410. Epub 2011 Oct 13. Cells Tissues Organs. 2012. PMID: 21997121 Free PMC article. Review.

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