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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: mueller holzner e. Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219944 Free PMC article.
Epigenetic stem cell signature in cancer.
Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young J, Jacobs I, Laird PW. Widschwendter M, et al. Nat Genet. 2007 Feb;39(2):157-8. doi: 10.1038/ng1941. Epub 2006 Dec 31. Nat Genet. 2007. PMID: 17200673
Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer.
Fiegl H, Jones A, Hauser-Kronberger C, Hutarew G, Reitsamer R, Jones RL, Dowsett M, Mueller-Holzner E, Windbichler G, Daxenbichler G, Goebel G, Ensinger C, Jacobs I, Widschwendter M. Fiegl H, et al. Among authors: mueller holzner e. Clin Cancer Res. 2008 Jun 1;14(11):3494-502. doi: 10.1158/1078-0432.CCR-07-4557. Clin Cancer Res. 2008. PMID: 18519782 Free article.
Methylated DNA collected by tampons--a new tool to detect endometrial cancer.
Fiegl H, Gattringer C, Widschwendter A, Schneitter A, Ramoni A, Sarlay D, Gaugg I, Goebel G, Müller HM, Mueller-Holzner E, Marth C, Widschwendter M. Fiegl H, et al. Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):882-8. Cancer Epidemiol Biomarkers Prev. 2004. PMID: 15159323
FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C. Akhoondi S, et al. Among authors: mueller holzner e. Cancer Res. 2007 Oct 1;67(19):9006-12. doi: 10.1158/0008-5472.CAN-07-1320. Cancer Res. 2007. PMID: 17909001
29 results