Meegan MJ - Search Results

1

Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects.

Barrett I, Carr M, O'Boyle N, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ. Barrett I, et al. Among authors: meegan mj. J Enzyme Inhib Med Chem. 2010 Apr;25(2):180-94. doi: 10.3109/14756360903169659. J Enzyme Inhib Med Chem. 2010. PMID: 20222762 Free article.

2

Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. J Med Chem. 2001 Mar 29;44(7):1072-84. doi: 10.1021/jm001119l. J Med Chem. 2001. PMID: 11297454

3

Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Anticancer Drug Des. 2001 Feb;16(1):57-69. Anticancer Drug Des. 2001. PMID: 11762645

4

Advances in the science of estrogen receptor modulation.

Meegan MJ, Lloyd DG. Meegan MJ, et al. Curr Med Chem. 2003 Feb;10(3):181-210. doi: 10.2174/0929867033368501. Curr Med Chem. 2003. PMID: 12570707 Review.

5

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.

Lloyd DG, Hughes RB, Zisterer DM, Williams DC, Fattorusso C, Catalanotti B, Campiani G, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. J Med Chem. 2004 Nov 4;47(23):5612-5. doi: 10.1021/jm0495834. J Med Chem. 2004. PMID: 15509159

6

Recent advances in estrogen receptor antagonists.

Lloyd DG, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. IDrugs. 2000 Jun;3(6):632-42. IDrugs. 2000. PMID: 16096926 No abstract available.

7

Considerations in compound database preparation--"hidden" impact on virtual screening results.

Knox AJ, Meegan MJ, Carta G, Lloyd DG. Knox AJ, et al. Among authors: meegan mj. J Chem Inf Model. 2005 Nov-Dec;45(6):1908-19. doi: 10.1021/ci050185z. J Chem Inf Model. 2005. PMID: 16309298

8

Estrogen receptors: molecular interactions, virtual screening and future prospects.

Knox AJ, Meegan MJ, Lloyd DG. Knox AJ, et al. Among authors: meegan mj. Curr Top Med Chem. 2006;6(3):217-43. doi: 10.2174/156802606776173438. Curr Top Med Chem. 2006. PMID: 16515479 Review.

9

Oncology exploration: charting cancer medicinal chemistry space.

Lloyd DG, Golfis G, Knox AJ, Fayne D, Meegan MJ, Oprea TI. Lloyd DG, et al. Among authors: meegan mj. Drug Discov Today. 2006 Feb;11(3-4):149-59. doi: 10.1016/S1359-6446(05)03688-3. Drug Discov Today. 2006. PMID: 16533713 Review.

10

Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor antagonists.

Lloyd DG, Smith HM, O'Sullivan T, Knox AS, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. Med Chem. 2006 Mar;2(2):147-68. doi: 10.2174/157340606776056142. Med Chem. 2006. PMID: 16787364

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