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The PARP inhibitor rucaparib blocks SARS-CoV-2 virus binding to cells and the immune reaction in models of COVID-19.
Papp H, Tóth E, Bóvári-Biri J, Bánfai K, Juhász P, Mahdi M, Russo LC, Bajusz D, Sipos A, Petri L, Szalai TV, Kemény Á, Madai M, Kuczmog A, Batta G, Mózner O, Vaskó D, Hirsch E, Bohus P, Méhes G, Tőzsér J, Curtin NJ, Helyes Z, Tóth A, Hoch NC, Jakab F, Keserű GM, Pongrácz JE, Bai P. Papp H, et al. Among authors: juhasz p. Br J Pharmacol. 2024 Dec;181(23):4782-4803. doi: 10.1111/bph.17305. Epub 2024 Aug 27. Br J Pharmacol. 2024. PMID: 39191429
Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability.
Jin H, Zhang C, Nagenborg J, Juhasz P, Ruder AV, Sikkink CJJM, Mees BME, Waring O, Sluimer JC, Neumann D, Goossens P, Donners MMPC, Mardinoglu A, Biessen EAL. Jin H, et al. Among authors: juhasz p. Cardiovasc Diabetol. 2024 Jul 8;23(1):240. doi: 10.1186/s12933-024-02339-3. Cardiovasc Diabetol. 2024. PMID: 38978031 Free PMC article.
Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia.
Pálinkás M, Szabó E, Kulin A, Mózner O, Rásonyi R, Juhász P, Nagy K, Várady G, Vörös D, Zámbó B, Sarkadi B, Poór G. Pálinkás M, et al. Among authors: juhasz p. Clin Exp Med. 2023 Aug;23(4):1277-1284. doi: 10.1007/s10238-022-00848-7. Epub 2022 Aug 8. Clin Exp Med. 2023. PMID: 35939175 Free PMC article.
Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage.
Jin H, Goossens P, Juhasz P, Eijgelaar W, Manca M, Karel JMH, Smirnov E, Sikkink CJJM, Mees BME, Waring O, van Kuijk K, Fazzi GE, Gijbels MJJ, Kutmon M, Evelo CTA, Hedin U, Daemen MJAP, Sluimer JC, Matic L, Biessen EAL. Jin H, et al. Among authors: juhasz p. Clin Transl Med. 2021 Jun;11(6):e458. doi: 10.1002/ctm2.458. Clin Transl Med. 2021. PMID: 34185408 Free PMC article.
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
Connor-Robson N, Booth H, Martin JG, Gao B, Li K, Doig N, Vowles J, Browne C, Klinger L, Juhasz P, Klein C, Cowley SA, Bolam P, Hirst W, Wade-Martins R. Connor-Robson N, et al. Among authors: juhasz p. Neurobiol Dis. 2019 Jul;127:512-526. doi: 10.1016/j.nbd.2019.04.005. Epub 2019 Apr 5. Neurobiol Dis. 2019. PMID: 30954703 Free PMC article.
125 results