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Page 1
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH, Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S. Rudolph V, et al. Among authors: hazen sl. Nat Med. 2010 Apr;16(4):470-4. doi: 10.1038/nm.2124. Epub 2010 Mar 21. Nat Med. 2010. PMID: 20305660 Free PMC article.
An abundant dysfunctional apolipoprotein A1 in human atheroma.
Huang Y, DiDonato JA, Levison BS, Schmitt D, Li L, Wu Y, Buffa J, Kim T, Gerstenecker GS, Gu X, Kadiyala CS, Wang Z, Culley MK, Hazen JE, Didonato AJ, Fu X, Berisha SZ, Peng D, Nguyen TT, Liang S, Chuang CC, Cho L, Plow EF, Fox PL, Gogonea V, Tang WH, Parks JS, Fisher EA, Smith JD, Hazen SL. Huang Y, et al. Among authors: hazen je, hazen sl. Nat Med. 2014 Feb;20(2):193-203. doi: 10.1038/nm.3459. Epub 2014 Jan 26. Nat Med. 2014. PMID: 24464187 Free PMC article.
Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling.
Mollenhauer M, Friedrichs K, Lange M, Gesenberg J, Remane L, Kerkenpaß C, Krause J, Schneider J, Ravekes T, Maass M, Halbach M, Peinkofer G, Saric T, Mehrkens D, Adam M, Deuschl FG, Lau D, Geertz B, Manchanda K, Eschenhagen T, Kubala L, Rudolph TK, Wu Y, Tang WHW, Hazen SL, Baldus S, Klinke A, Rudolph V. Mollenhauer M, et al. Among authors: hazen sl. Circ Res. 2017 Jun 23;121(1):56-70. doi: 10.1161/CIRCRESAHA.117.310870. Epub 2017 Apr 12. Circ Res. 2017. PMID: 28404615 Free PMC article.
Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.
Kim HW, Blomkalns AL, Ogbi M, Thomas M, Gavrila D, Neltner BS, Cassis LA, Thompson RW, Weiss RM, Lindower PD, Blanco VM, McCormick ML, Daugherty A, Fu X, Hazen SL, Stansfield BK, Huo Y, Fulton DJ, Chatterjee T, Weintraub NL. Kim HW, et al. Among authors: hazen sl. Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1168-H1179. doi: 10.1152/ajpheart.00296.2017. Epub 2017 Sep 29. Am J Physiol Heart Circ Physiol. 2017. PMID: 28971841 Free PMC article.
Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.
Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S. Klinke A, et al. Among authors: hazen sl. JCI Insight. 2018 Jun 7;3(11):e97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875311 Free PMC article.
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Roberts AB, Gu X, Buffa JA, Hurd AG, Wang Z, Zhu W, Gupta N, Skye SM, Cody DB, Levison BS, Barrington WT, Russell MW, Reed JM, Duzan A, Lang JM, Fu X, Li L, Myers AJ, Rachakonda S, DiDonato JA, Brown JM, Gogonea V, Lusis AJ, Garcia-Garcia JC, Hazen SL. Roberts AB, et al. Among authors: hazen sl. Nat Med. 2018 Sep;24(9):1407-1417. doi: 10.1038/s41591-018-0128-1. Epub 2018 Aug 6. Nat Med. 2018. PMID: 30082863 Free PMC article.
A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.
Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HM, Ischiropoulos H, Hazen SL. Brennan ML, et al. Among authors: hazen sl. J Biol Chem. 2002 May 17;277(20):17415-27. doi: 10.1074/jbc.M112400200. Epub 2002 Feb 27. J Biol Chem. 2002. PMID: 11877405 Free article.
536 results