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Noncoding RNAs: biology and applications-a Keystone Symposia report.
Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, Chen CK, Wilusz JE, Lempradl A, McGeary SE, Wahba L, Pyle AM, Hargrove AE, Simon MD, Marcia M, Przanowska RK, Chang HY, Jaffrey SR, Contreras LM, Chen Q, Shi J, Mendell JT, He L, Song E, Rinn JL, Lalwani MK, Kalem MC, Chuong EB, Maquat LE, Liu X. Cable J, et al. Among authors: simon md. Ann N Y Acad Sci. 2021 Dec;1506(1):118-141. doi: 10.1111/nyas.14713. Epub 2021 Nov 17. Ann N Y Acad Sci. 2021. PMID: 34791665 Free PMC article. Review.
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Youngblood MW, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Youngblood MW, et al. Nat Commun. 2023 Oct 7;14(1):6279. doi: 10.1038/s41467-023-41926-y. Nat Commun. 2023. PMID: 37805627 Free PMC article.
E-box independent chromatin recruitment turns MYOD into a transcriptional repressor.
Nicoletti C, Massenet J, Pintado-Urbanc AP, Connor LJ, Nicolau M, Sundar S, Xu M, Schmitt A, Zhang W, Fang Z, Chan TCI, Tapscott SJ, Cheung TH, Simon MD, Caputo L, Puri PL. Nicoletti C, et al. Among authors: simon md. bioRxiv [Preprint]. 2024 Dec 5:2024.12.05.627024. doi: 10.1101/2024.12.05.627024. bioRxiv. 2024. PMID: 39677796 Free PMC article. Preprint.
Rapid folding of nascent RNA regulates eukaryotic RNA biogenesis.
Schärfen L, Vock IW, Simon MD, Neugebauer KM. Schärfen L, et al. Among authors: simon md. bioRxiv [Preprint]. 2024 Nov 26:2024.11.26.625435. doi: 10.1101/2024.11.26.625435. bioRxiv. 2024. PMID: 39651172 Free PMC article. Preprint.
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.
Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Boddu PC, et al. Among authors: simon md. Mol Cell. 2024 Apr 18;84(8):1475-1495.e18. doi: 10.1016/j.molcel.2024.02.032. Epub 2024 Mar 22. Mol Cell. 2024. PMID: 38521065
105 results