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Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.
Brigman JL, Wright T, Talani G, Prasad-Mulcare S, Jinde S, Seabold GK, Mathur P, Davis MI, Bock R, Gustin RM, Colbran RJ, Alvarez VA, Nakazawa K, Delpire E, Lovinger DM, Holmes A. Brigman JL, et al. Among authors: davis mi. J Neurosci. 2010 Mar 31;30(13):4590-600. doi: 10.1523/JNEUROSCI.0640-10.2010. J Neurosci. 2010. PMID: 20357110 Free PMC article.
The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels.
Godlewski G, Offertáler L, Osei-Hyiaman D, Mo FM, Harvey-White J, Liu J, Davis MI, Zhang L, Razdan RK, Milman G, Pacher P, Mukhopadhyay P, Lovinger DM, Kunos G. Godlewski G, et al. Among authors: davis mi. J Pharmacol Exp Ther. 2009 Jan;328(1):351-61. doi: 10.1124/jpet.108.144717. Epub 2008 Oct 15. J Pharmacol Exp Ther. 2009. PMID: 18923087 Free PMC article.
117 results