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The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.
Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. Christov PP, et al. Among authors: kozekova a. Chem Res Toxicol. 2010 Jun 21;23(6):1076-88. doi: 10.1021/tx100053n. Chem Res Toxicol. 2010. PMID: 20377178 Free PMC article.
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ. Christov PP, et al. Among authors: kozekova a. Chem Res Toxicol. 2010 Aug 16;23(8):1330-41. doi: 10.1021/tx100082e. Chem Res Toxicol. 2010. PMID: 20578729 Free PMC article.
Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.
Cho YJ, Kim HY, Huang H, Slutsky A, Minko IG, Wang H, Nechev LV, Kozekov ID, Kozekova A, Tamura P, Jacob J, Voehler M, Harris TM, Lloyd RS, Rizzo CJ, Stone MP. Cho YJ, et al. Among authors: kozekova a. J Am Chem Soc. 2005 Dec 21;127(50):17686-96. doi: 10.1021/ja053897e. J Am Chem Soc. 2005. PMID: 16351098 Free PMC article.
19 results