Turesky RJ - Search Results

1

The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.

Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. Christov PP, et al. Among authors: turesky rj. Chem Res Toxicol. 2010 Jun 21;23(6):1076-88. doi: 10.1021/tx100053n. Chem Res Toxicol. 2010. PMID: 20377178 Free PMC article.

2

Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine.

Turesky RJ, Rossi SC, Welti DH, Lay JO Jr, Kadlubar FF. Turesky RJ, et al. Chem Res Toxicol. 1992 Jul-Aug;5(4):479-90. doi: 10.1021/tx00028a005. Chem Res Toxicol. 1992. PMID: 1391614

3

Metabolism of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay.

Snyderwine EG, Welti DH, Fay LB, Würzner HP, Turesky RJ. Snyderwine EG, et al. Among authors: turesky rj. Chem Res Toxicol. 1992 Nov-Dec;5(6):843-51. doi: 10.1021/tx00030a018. Chem Res Toxicol. 1992. PMID: 1489936

4

DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5- f]quinoline at the C-8 and N2 atoms of guanine.

Turesky RJ, Markovic J. Turesky RJ, et al. Chem Res Toxicol. 1994 Nov-Dec;7(6):752-61. doi: 10.1021/tx00042a007. Chem Res Toxicol. 1994. PMID: 7696529

5

Formation and differential removal of C-8 and N2-guanine adducts of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in the liver, kidney, and colorectum of the rat.

Turesky RJ, Markovic J, Aeschlimann JM. Turesky RJ, et al. Chem Res Toxicol. 1996 Mar;9(2):397-402. doi: 10.1021/tx950131r. Chem Res Toxicol. 1996. PMID: 8839041

6

DNA adduct formation of the food-derived mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay.

Turesky RJ, Gremaud E, Markovic J, Snyderwine EG. Turesky RJ, et al. Chem Res Toxicol. 1996 Mar;9(2):403-8. doi: 10.1021/tx950132j. Chem Res Toxicol. 1996. PMID: 8839042

7

Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.

Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP. Turesky RJ, et al. Chem Res Toxicol. 1998 Aug;11(8):925-36. doi: 10.1021/tx980022n. Chem Res Toxicol. 1998. PMID: 9705755

8

Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2.

Turesky RJ, Constable A, Fay LB, Guengerich FP. Turesky RJ, et al. Cancer Lett. 1999 Sep 1;143(2):109-12. doi: 10.1016/s0304-3835(99)00137-8. Cancer Lett. 1999. PMID: 10503887

9

Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype.

Guengerich FP, Parikh A, Turesky RJ, Josephy PD. Guengerich FP, et al. Among authors: turesky rj. Mutat Res. 1999 Jul 16;428(1-2):115-24. doi: 10.1016/s1383-5742(99)00039-3. Mutat Res. 1999. PMID: 10517985 Review.

10

Determination of in vitro- and in vivo-formed DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline by capillary liquid chromatography/microelectrospray mass spectrometry.

Gangl ET, Turesky RJ, Vouros P. Gangl ET, et al. Among authors: turesky rj. Chem Res Toxicol. 1999 Oct;12(10):1019-27. doi: 10.1021/tx990060m. Chem Res Toxicol. 1999. PMID: 10525280

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