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Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G. Tan SM, et al. Among authors: rajendran p. J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8. J Pharmacol Exp Ther. 2010. PMID: 20378717
Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades.
Sikka S, Shanmugam MK, Siveen KS, Ong TH, Yang MH, Lee JH, Rajendran P, Chinnathambi A, Alharbi SA, Alahmadi TA, Vali S, Kumar AP, Sethi G, Wang L, Hui KM, Ahn KS. Sikka S, et al. Among authors: rajendran p. Eur J Pharmacol. 2021 Sep 5;906:174274. doi: 10.1016/j.ejphar.2021.174274. Epub 2021 Jun 17. Eur J Pharmacol. 2021. PMID: 34146587
Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.
Kannaiyan R, Hay HS, Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Chng WJ, Sethi G. Kannaiyan R, et al. Among authors: rajendran p. Br J Pharmacol. 2011 Nov;164(5):1506-21. doi: 10.1111/j.1476-5381.2011.01449.x. Br J Pharmacol. 2011. PMID: 21506956 Free PMC article.
340 results