Schiöth HB - Search Results

1

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children.

Almén MS, Jacobsson JA, Shaik JH, Olszewski PK, Cedernaes J, Alsiö J, Sreedharan S, Levine AS, Fredriksson R, Marcus C, Schiöth HB. Almén MS, et al. Among authors: schioth hb. BMC Med Genet. 2010 Apr 9;11:58. doi: 10.1186/1471-2350-11-58. BMC Med Genet. 2010. PMID: 20380707 Free PMC article.

2

One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology.

Ringholm A, Fredriksson R, Poliakova N, Yan YL, Postlethwait JH, Larhammar D, Schiöth HB. Ringholm A, et al. Among authors: schioth hb. J Neurochem. 2002 Jul;82(1):6-18. doi: 10.1046/j.1471-4159.2002.00934.x. J Neurochem. 2002. PMID: 12091460 Free article.

3

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.

Fredriksson R, Lagerström MC, Höglund PJ, Schiöth HB. Fredriksson R, et al. Among authors: schioth hb. FEBS Lett. 2002 Nov 20;531(3):407-14. doi: 10.1016/s0014-5793(02)03574-3. FEBS Lett. 2002. PMID: 12435584 Free article.

4

There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.

Fredriksson R, Gloriam DE, Höglund PJ, Lagerström MC, Schiöth HB. Fredriksson R, et al. Among authors: schioth hb. Biochem Biophys Res Commun. 2003 Feb 14;301(3):725-34. doi: 10.1016/s0006-291x(03)00026-3. Biochem Biophys Res Commun. 2003. PMID: 12565841

5

Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system.

Ringholm A, Klovins J, Fredriksson R, Poliakova N, Larson ET, Kukkonen JP, Larhammar D, Schiöth HB. Ringholm A, et al. Among authors: schioth hb. Eur J Biochem. 2003 Jan;270(2):213-21. doi: 10.1046/j.1432-1033.2003.03371.x. Eur J Biochem. 2003. PMID: 12605672 Free article.

6

Association of feather colour with constitutively active melanocortin 1 receptors in chicken.

Ling MK, Lagerström MC, Fredriksson R, Okimoto R, Mundy NI, Takeuchi S, Schiöth HB. Ling MK, et al. Among authors: schioth hb. Eur J Biochem. 2003 Apr;270(7):1441-9. doi: 10.1046/j.1432-1033.2003.03506.x. Eur J Biochem. 2003. PMID: 12653999 Free article.

7

Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates.

Schiöth HB, Raudsepp T, Ringholm A, Fredriksson R, Takeuchi S, Larhammar D, Chowdhary BP. Schiöth HB, et al. Genomics. 2003 May;81(5):504-9. doi: 10.1016/s0888-7543(03)00028-4. Genomics. 2003. PMID: 12706108

8

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.

Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB. Fredriksson R, et al. Among authors: schioth hb. Mol Pharmacol. 2003 Jun;63(6):1256-72. doi: 10.1124/mol.63.6.1256. Mol Pharmacol. 2003. PMID: 12761335

9

Functional role, structure, and evolution of the melanocortin-4 receptor.

Schiöth HB, Lagerström MC, Watanobe H, Jonsson L, Vergoni AV, Ringholm A, Skarphedinsson JO, Skuladottir GV, Klovins J, Fredriksson R. Schiöth HB, et al. Ann N Y Acad Sci. 2003 Jun;994:74-83. doi: 10.1111/j.1749-6632.2003.tb03164.x. Ann N Y Acad Sci. 2003. PMID: 12851300 Review.

10

High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3.

Lagerström MC, Klovins J, Fredriksson R, Fridmanis D, Haitina T, Ling MK, Berglund MM, Schiöth HB. Lagerström MC, et al. Among authors: schioth hb. J Biol Chem. 2003 Dec 19;278(51):51521-6. doi: 10.1074/jbc.M307683200. Epub 2003 Sep 30. J Biol Chem. 2003. PMID: 14523020 Free article.

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