Xu Z - Search Results

1

3,5-Diaryl-1H-pyrazole as a molecular scaffold for the synthesis of apoptosis-inducing agents.

Shaw AY, Liau HH, Lu PJ, Yang CN, Lee CH, Chen JY, Xu Z, Flynn G. Shaw AY, et al. Among authors: xu z. Bioorg Med Chem. 2010 May 1;18(9):3270-8. doi: 10.1016/j.bmc.2010.03.016. Epub 2010 Mar 16. Bioorg Med Chem. 2010. PMID: 20381360

2

Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines.

Xu Z, Dietrich J, Shaw AY, Hulme C. Xu Z, et al. Tetrahedron Lett. 2010 Aug 25;51(34):4566-4569. doi: 10.1016/j.tetlet.2010.06.116. Tetrahedron Lett. 2010. PMID: 20706616 Free PMC article.

3

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines.

Xu Z, Shaw AY, Dietrich J, Cappelli AP, Nichol G, Hulme C. Xu Z, et al. Mol Divers. 2012 Feb;16(1):73-9. doi: 10.1007/s11030-011-9354-x. Epub 2012 Jan 12. Mol Divers. 2012. PMID: 22237832 Free PMC article.

4

Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes.

Xu Z, Shaw AY, Nichol GS, Cappelli AP, Hulme C. Xu Z, et al. Mol Divers. 2012 Aug;16(3):607-12. doi: 10.1007/s11030-012-9374-1. Epub 2012 May 24. Mol Divers. 2012. PMID: 22622389

5

Ugi/Robinson-Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles.

Shaw AY, Xu Z, Hulme C. Shaw AY, et al. Among authors: xu z. Tetrahedron Lett. 2012 Apr 11;53(15):1998-2000. doi: 10.1016/j.tetlet.2012.02.030. Epub 2012 Feb 13. Tetrahedron Lett. 2012. PMID: 23559684 Free PMC article.

6

Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.

He LJ, Yang DL, Li SQ, Zhang YJ, Tang Y, Lei J, Frett B, Lin HK, Li HY, Chen ZZ, Xu ZG. He LJ, et al. Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908. doi: 10.1016/j.bmc.2018.06.010. Epub 2018 Jun 12. Bioorg Med Chem. 2018. PMID: 29921474 Free PMC article.

7

Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents.

Xu J, Tan HB, Zhang YJ, Tang DY, Zhan F, Li HY, Chen ZZ, Xu ZG. Xu J, et al. Sci Rep. 2020 Jun 9;10(1):9281. doi: 10.1038/s41598-020-66137-z. Sci Rep. 2020. PMID: 32518332 Free PMC article.

8

Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy.

Ran K, Li Y, Zhang YM, Tang DY, Chen ZZ, Xu ZG, Zhang L, Wang BC, Huang JH. Ran K, et al. Bioorg Chem. 2024 Dec;153:107929. doi: 10.1016/j.bioorg.2024.107929. Epub 2024 Nov 2. Bioorg Chem. 2024. PMID: 39509789

9

Discovery of fused benzimidazole-imidazole autophagic flux inhibitors for treatment of triple-negative breast cancer.

Yang DL, Zhang YJ, Lei J, Li SQ, He LJ, Tang DY, Xu C, Zhang LT, Wen J, Lin HK, Li HY, Chen ZZ, Xu ZG. Yang DL, et al. Eur J Med Chem. 2022 Oct 5;240:114565. doi: 10.1016/j.ejmech.2022.114565. Epub 2022 Jun 26. Eur J Med Chem. 2022. PMID: 35797901

10

Highly potent Platinum(IV) complexes with multiple-bond ligands targeting mitochondria to overcome cisplatin resistance.

Fang B, Chen X, Zhou X, Hu X, Luo Y, Xu Z, Zhou CH, Meng JP, Chen ZZ, Hu C. Fang B, et al. Among authors: xu z. Eur J Med Chem. 2023 Mar 15;250:115235. doi: 10.1016/j.ejmech.2023.115235. Epub 2023 Feb 25. Eur J Med Chem. 2023. PMID: 36863226

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