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Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na+ channel.
Zhang Y, Wang T, Ma A, Zhou X, Gui J, Wan H, Shi R, Huang C, Grace AA, Huang CL, Trump D, Zhang H, Zimmer T, Lei M. Zhang Y, et al. Among authors: zimmer t. Acta Physiol (Oxf). 2008 Dec;194(4):311-23. doi: 10.1111/j.1748-1716.2008.01883.x. Epub 2008 Jul 24. Acta Physiol (Oxf). 2008. PMID: 18616619 Free PMC article.
SCN5A channelopathies--an update on mutations and mechanisms.
Zimmer T, Surber R. Zimmer T, et al. Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):120-36. doi: 10.1016/j.pbiomolbio.2008.10.005. Epub 2008 Nov 5. Prog Biophys Mol Biol. 2008. PMID: 19027780 Free article. Review.
Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart.
Tarradas A, Pinsach-Abuin ML, Mackintosh C, Llorà-Batlle O, Pérez-Serra A, Batlle M, Pérez-Villa F, Zimmer T, Garcia-Bassets I, Brugada R, Beltran-Alvarez P, Pagans S. Tarradas A, et al. Among authors: zimmer t. J Mol Cell Cardiol. 2017 Jan;102:74-82. doi: 10.1016/j.yjmcc.2016.10.013. Epub 2016 Nov 26. J Mol Cell Cardiol. 2017. PMID: 27894866 Free article.
Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel.
Beltran-Alvarez P, Espejo A, Schmauder R, Beltran C, Mrowka R, Linke T, Batlle M, Pérez-Villa F, Pérez GJ, Scornik FS, Benndorf K, Pagans S, Zimmer T, Brugada R. Beltran-Alvarez P, et al. Among authors: zimmer t. FEBS Lett. 2013 Oct 1;587(19):3159-65. doi: 10.1016/j.febslet.2013.07.043. Epub 2013 Jul 31. FEBS Lett. 2013. PMID: 23912080 Free article.
Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.
Freyermuth F, Rau F, Kokunai Y, Linke T, Sellier C, Nakamori M, Kino Y, Arandel L, Jollet A, Thibault C, Philipps M, Vicaire S, Jost B, Udd B, Day JW, Duboc D, Wahbi K, Matsumura T, Fujimura H, Mochizuki H, Deryckere F, Kimura T, Nukina N, Ishiura S, Lacroix V, Campan-Fournier A, Navratil V, Chautard E, Auboeuf D, Horie M, Imoto K, Lee KY, Swanson MS, de Munain AL, Inada S, Itoh H, Nakazawa K, Ashihara T, Wang E, Zimmer T, Furling D, Takahashi MP, Charlet-Berguerand N. Freyermuth F, et al. Among authors: zimmer t. Nat Commun. 2016 Apr 11;7:11067. doi: 10.1038/ncomms11067. Nat Commun. 2016. PMID: 27063795 Free PMC article.
188 results