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PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Hou X, Kumar A, Lee C, Wang B, Arjunan P, Dong L, Maminishkis A, Tang Z, Li Y, Zhang F, Zhang SZ, Wardega P, Chakrabarty S, Liu B, Wu Z, Colosi P, Fariss RN, Lennartsson J, Nussenblatt R, Gutkind JS, Cao Y, Li X. Hou X, et al. Among authors: li y, li x. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12216-21. doi: 10.1073/pnas.1004143107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566880 Free PMC article.
Complicated life, complicated VEGF-B.
Li X, Kumar A, Zhang F, Lee C, Tang Z. Li X, et al. Trends Mol Med. 2012 Feb;18(2):119-27. doi: 10.1016/j.molmed.2011.11.006. Epub 2011 Dec 15. Trends Mol Med. 2012. PMID: 22178229 Review.
Proliferative and survival effects of PUMA promote angiogenesis.
Zhang F, Li Y, Tang Z, Kumar A, Lee C, Zhang L, Zhu C, Klotzsche-von Ameln A, Wang B, Gao Z, Zhang S, Langer HF, Hou X, Jensen L, Ma W, Wong W, Chavakis T, Liu Y, Cao Y, Li X. Zhang F, et al. Among authors: li y, li x. Cell Rep. 2012 Nov 29;2(5):1272-85. doi: 10.1016/j.celrep.2012.09.023. Epub 2012 Nov 1. Cell Rep. 2012. PMID: 23122957 Free article.
VEGF-B: a survival, or an angiogenic factor?
Li X, Lee C, Tang Z, Zhang F, Arjunan P, Li Y, Hou X, Kumar A, Dong L. Li X, et al. Among authors: li y. Cell Adh Migr. 2009 Oct-Dec;3(4):322-7. doi: 10.4161/cam.3.4.9459. Epub 2009 Oct 3. Cell Adh Migr. 2009. PMID: 19684473 Free PMC article. Review.
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X. Tang Z, et al. Among authors: li y, li x. J Exp Med. 2010 Apr 12;207(4):867-80. doi: 10.1084/jem.20091704. Epub 2010 Mar 15. J Exp Med. 2010. PMID: 20231377 Free PMC article.
Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
Segarra M, Ohnuki H, Maric D, Salvucci O, Hou X, Kumar A, Li X, Tosato G. Segarra M, et al. Among authors: li x. Blood. 2012 Nov 8;120(19):4104-15. doi: 10.1182/blood-2012-02-410076. Epub 2012 Sep 24. Blood. 2012. PMID: 23007403 Free PMC article.
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