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Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy.
Spernyak JA, White WH 3rd, Ethirajan M, Patel NJ, Goswami L, Chen Y, Turowski S, Missert JR, Batt C, Mazurchuk R, Pandey RK. Spernyak JA, et al. Among authors: goswami l. Bioconjug Chem. 2010 May 19;21(5):828-35. doi: 10.1021/bc9005317. Bioconjug Chem. 2010. PMID: 20387862 Free PMC article.
Regioselective synthesis and photophysical and electrochemical studies of 20-substituted cyanine dye-purpurinimide conjugates: incorporation of Ni(II) into the conjugate enhances its tumor-uptake and fluorescence-imaging ability.
Ethirajan M, Chen P, Ohulchanskyy TY, Goswami LN, Gupta A, Srivatsan A, Dobhal MP, Missert JR, Prasad PN, Kadish KM, Pandey RK. Ethirajan M, et al. Chemistry. 2013 May 17;19(21):6670-84. doi: 10.1002/chem.201203867. Epub 2013 Mar 22. Chemistry. 2013. PMID: 23526622
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