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New approach methods to improve human health risk assessment of thyroid hormone system disruption-a PARC project.
Ramhøj L, Axelstad M, Baert Y, Cañas-Portilla AI, Chalmel F, Dahmen L, De La Vieja A, Evrard B, Haigis AC, Hamers T, Heikamp K, Holbech H, Iglesias-Hernandez P, Knapen D, Marchandise L, Morthorst JE, Nikolov NG, Nissen ACVE, Oelgeschlaeger M, Renko K, Rogiers V, Schüürmann G, Stinckens E, Stub MH, Torres-Ruiz M, Van Duursen M, Vanhaecke T, Vergauwen L, Wedebye EB, Svingen T. Ramhøj L, et al. Front Toxicol. 2023 May 17;5:1189303. doi: 10.3389/ftox.2023.1189303. eCollection 2023. Front Toxicol. 2023. PMID: 37265663 Free PMC article. Review.
3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
Antolino-Lobo I, Meulenbelt J, Nijmeijer SM, Maas-Bakker RF, Meijerman I, van den Berg M, van Duursen MB. Antolino-Lobo I, et al. Among authors: van den berg m, van duursen mb. Toxicol Lett. 2011 May 30;203(1):82-91. doi: 10.1016/j.toxlet.2011.03.007. Epub 2011 Mar 22. Toxicol Lett. 2011. PMID: 21402137
70 results