O'Riordan KJ - Search Results

1

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death.

Pehar M, O'Riordan KJ, Burns-Cusato M, Andrzejewski ME, del Alcazar CG, Burger C, Scrable H, Puglielli L. Pehar M, et al. Aging Cell. 2010 Apr;9(2):174-90. doi: 10.1111/j.1474-9726.2010.00547.x. Aging Cell. 2010. PMID: 20409077 Free PMC article.

2

The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism.

Li M, Pehar M, Liu Y, Bhattacharyya A, Zhang SC, O'Riordan KJ, Burger C, D'Adamio L, Puglielli L. Li M, et al. Neurobiol Aging. 2015 Oct;36(10):2725-36. doi: 10.1016/j.neurobiolaging.2015.06.021. Epub 2015 Jun 21. Neurobiol Aging. 2015. PMID: 26174856 Free PMC article.

3

Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse.

Peng Y, Kim MJ, Hullinger R, O'Riordan KJ, Burger C, Pehar M, Puglielli L. Peng Y, et al. Brain. 2016 Mar;139(Pt 3):937-52. doi: 10.1093/brain/awv385. Epub 2016 Jan 19. Brain. 2016. PMID: 26787453 Free PMC article.

4

Environmental enrichment improves learning and memory and long-term potentiation in young adult rats through a mechanism requiring mGluR5 signaling and sustained activation of p70s6k.

Hullinger R, O'Riordan K, Burger C. Hullinger R, et al. Neurobiol Learn Mem. 2015 Nov;125:126-34. doi: 10.1016/j.nlm.2015.08.006. Epub 2015 Sep 2. Neurobiol Learn Mem. 2015. PMID: 26341144 Free PMC article.

5

Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity.

Cortese GP, Olin A, O'Riordan K, Hullinger R, Burger C. Cortese GP, et al. Neurobiol Aging. 2018 Mar;63:1-11. doi: 10.1016/j.neurobiolaging.2017.11.004. Epub 2017 Nov 16. Neurobiol Aging. 2018. PMID: 29207276 Free PMC article.

6

Induction of Metabotropic Glutamate Receptor-Mediated Long-Term Depression in the Hippocampal Schaffer Collateral Pathway of Aging Rats.

Gimse KE, O'Riordan K, Burger C. Gimse KE, et al. Methods Mol Biol. 2019;1941:93-105. doi: 10.1007/978-1-4939-9077-1_8. Methods Mol Biol. 2019. PMID: 30707430

7

Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.

Potter WB, Basu T, O'Riordan KJ, Kirchner A, Rutecki P, Burger C, Roopra A. Potter WB, et al. PLoS Biol. 2013;11(8):e1001627. doi: 10.1371/journal.pbio.1001627. Epub 2013 Aug 13. PLoS Biol. 2013. PMID: 23966835 Free PMC article.

8

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c.

Gerstein H, O'Riordan K, Osting S, Schwarz M, Burger C. Gerstein H, et al. Neurobiol Learn Mem. 2012 Jan;97(1):17-29. doi: 10.1016/j.nlm.2011.08.009. Epub 2011 Sep 14. Neurobiol Learn Mem. 2012. PMID: 21945599 Free PMC article.

9

The role of Homer1c in metabotropic glutamate receptor-dependent long-term potentiation.

O'Riordan K, Gerstein H, Hullinger R, Burger C. O'Riordan K, et al. Hippocampus. 2014 Jan;24(1):1-6. doi: 10.1002/hipo.22222. Epub 2013 Nov 23. Hippocampus. 2014. PMID: 24167026 Free PMC article.

10

Pin1 and PKMzeta sequentially control dendritic protein synthesis.

Westmark PR, Westmark CJ, Wang S, Levenson J, O'Riordan KJ, Burger C, Malter JS. Westmark PR, et al. Sci Signal. 2010 Mar 9;3(112):ra18. doi: 10.1126/scisignal.2000451. Sci Signal. 2010. PMID: 20215645 Free PMC article.

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