Gerwick WH - Search Results

1

The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria.

Jones AC, Monroe EA, Eisman EB, Gerwick L, Sherman DH, Gerwick WH. Jones AC, et al. Among authors: gerwick l, gerwick wh. Nat Prod Rep. 2010 Jul;27(7):1048-65. doi: 10.1039/c000535e. Epub 2010 May 4. Nat Prod Rep. 2010. PMID: 20442916 Review.

2

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit.

Chang Z, Flatt P, Gerwick WH, Nguyen VA, Willis CL, Sherman DH. Chang Z, et al. Among authors: gerwick wh. Gene. 2002 Aug 21;296(1-2):235-47. doi: 10.1016/s0378-1119(02)00860-0. Gene. 2002. PMID: 12383521

3

Marine natural products as novel antioxidant prototypes.

Takamatsu S, Hodges TW, Rajbhandari I, Gerwick WH, Hamann MT, Nagle DG. Takamatsu S, et al. Among authors: gerwick wh. J Nat Prod. 2003 May;66(5):605-8. doi: 10.1021/np0204038. J Nat Prod. 2003. PMID: 12762791 Free PMC article.

4

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

Chang Z, Sitachitta N, Rossi JV, Roberts MA, Flatt PM, Jia J, Sherman DH, Gerwick WH. Chang Z, et al. Among authors: gerwick wh. J Nat Prod. 2004 Aug;67(8):1356-67. doi: 10.1021/np0499261. J Nat Prod. 2004. PMID: 15332855

5

Characterization of the initial enzymatic steps of barbamide biosynthesis.

Flatt PM, O'Connell SJ, McPhail KL, Zeller G, Willis CL, Sherman DH, Gerwick WH. Flatt PM, et al. Among authors: gerwick wh. J Nat Prod. 2006 Jun;69(6):938-44. doi: 10.1021/np050523q. J Nat Prod. 2006. PMID: 16792414

6

Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair.

Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. Gu L, et al. Among authors: gerwick wh. J Am Chem Soc. 2006 Jul 19;128(28):9014-5. doi: 10.1021/ja0626382. J Am Chem Soc. 2006. PMID: 16834357

7

Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp.

Linington RG, Gonzalez J, Ureña LD, Romero LI, Ortega-Barría E, Gerwick WH. Linington RG, et al. Among authors: gerwick wh. J Nat Prod. 2007 Mar;70(3):397-401. doi: 10.1021/np0605790. Epub 2007 Mar 1. J Nat Prod. 2007. PMID: 17328572

8

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.

Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. Geders TW, et al. Among authors: gerwick wh. J Biol Chem. 2007 Dec 7;282(49):35954-63. doi: 10.1074/jbc.M703921200. Epub 2007 Oct 10. J Biol Chem. 2007. PMID: 17928301 Free article.

9

GNAT-like strategy for polyketide chain initiation.

Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. Gu L, et al. Among authors: gerwick wh. Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790. Science. 2007. PMID: 17991863

10

Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.

Linington RG, Edwards DJ, Shuman CF, McPhail KL, Matainaho T, Gerwick WH. Linington RG, et al. Among authors: gerwick wh. J Nat Prod. 2008 Jan;71(1):22-7. doi: 10.1021/np070280x. Epub 2007 Dec 29. J Nat Prod. 2008. PMID: 18163584 Free PMC article.

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