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Signal peptide mutations in RANK prevent downstream activation of NF-κB.
Crockett JC, Mellis DJ, Shennan KI, Duthie A, Greenhorn J, Wilkinson DI, Ralston SH, Helfrich MH, Rogers MJ. Crockett JC, et al. Among authors: mellis dj. J Bone Miner Res. 2011 Aug;26(8):1926-38. doi: 10.1002/jbmr.399. J Bone Miner Res. 2011. PMID: 21472776 Free PMC article.
Transfection of osteoclasts and osteoclast precursors.
Crockett JC, Mellis DJ, Taylor A. Crockett JC, et al. Among authors: mellis dj. Methods Mol Biol. 2012;816:205-22. doi: 10.1007/978-1-61779-415-5_14. Methods Mol Biol. 2012. PMID: 22130931
RANK-dependent autosomal recessive osteopetrosis: characterization of five new cases with novel mutations.
Pangrazio A, Cassani B, Guerrini MM, Crockett JC, Marrella V, Zammataro L, Strina D, Schulz A, Schlack C, Kornak U, Mellis DJ, Duthie A, Helfrich MH, Durandy A, Moshous D, Vellodi A, Chiesa R, Veys P, Lo Iacono N, Vezzoni P, Fischer A, Villa A, Sobacchi C. Pangrazio A, et al. Among authors: mellis dj. J Bone Miner Res. 2012 Feb;27(2):342-51. doi: 10.1002/jbmr.559. J Bone Miner Res. 2012. PMID: 22271396 Free PMC article.
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations.
Guerrini MM, Sobacchi C, Cassani B, Abinun M, Kilic SS, Pangrazio A, Moratto D, Mazzolari E, Clayton-Smith J, Orchard P, Coxon FP, Helfrich MH, Crockett JC, Mellis D, Vellodi A, Tezcan I, Notarangelo LD, Rogers MJ, Vezzoni P, Villa A, Frattini A. Guerrini MM, et al. Am J Hum Genet. 2008 Jul;83(1):64-76. doi: 10.1016/j.ajhg.2008.06.015. Am J Hum Genet. 2008. PMID: 18606301 Free PMC article.
Generation and culture of osteoclasts.
Marino S, Logan JG, Mellis D, Capulli M. Marino S, et al. Bonekey Rep. 2014 Sep 10;3:570. doi: 10.1038/bonekey.2014.65. eCollection 2014. Bonekey Rep. 2014. PMID: 25228983 Free PMC article.
Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis.
Mellis D, Staines KA, Peluso S, Georgiou IC, Dora N, Kubiak M, Van't Hof R, Grillo M, Farquharson C, Kinsella E, Thornburn A, Ralston SH, Salter DM, Riobo-Del Galdo NA, Hill RE, Ditzel M. Mellis D, et al. PLoS Genet. 2021 Apr 5;17(4):e1009275. doi: 10.1371/journal.pgen.1009275. eCollection 2021 Apr. PLoS Genet. 2021. PMID: 33819267 Free PMC article.
16 results