Venkatesan R - Search Results

1

Crystal structure of liganded rat peroxisomal multifunctional enzyme type 1: a flexible molecule with two interconnected active sites.

Kasaragod P, Venkatesan R, Kiema TR, Hiltunen JK, Wierenga RK. Kasaragod P, et al. Among authors: venkatesan r. J Biol Chem. 2010 Jul 30;285(31):24089-98. doi: 10.1074/jbc.M110.117606. Epub 2010 May 12. J Biol Chem. 2010. PMID: 20463028 Free PMC article.

2

Triosephosphate isomerase: a highly evolved biocatalyst.

Wierenga RK, Kapetaniou EG, Venkatesan R. Wierenga RK, et al. Among authors: venkatesan r. Cell Mol Life Sci. 2010 Dec;67(23):3961-82. doi: 10.1007/s00018-010-0473-9. Epub 2010 Aug 7. Cell Mol Life Sci. 2010. PMID: 20694739 Free PMC article. Review.

3

High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: the conformational flexibility of the catalytic glutamate in its closed, liganded active site.

Venkatesan R, Alahuhta M, Pihko PM, Wierenga RK. Venkatesan R, et al. Protein Sci. 2011 Aug;20(8):1387-97. doi: 10.1002/pro.667. Epub 2011 Jul 7. Protein Sci. 2011. PMID: 21633986 Free PMC article.

4

The enolization chemistry of a thioester-dependent racemase: the 1.4 Å crystal structure of a reaction intermediate complex characterized by detailed QM/MM calculations.

Sharma S, Bhaumik P, Schmitz W, Venkatesan R, Hiltunen JK, Conzelmann E, Juffer AH, Wierenga RK. Sharma S, et al. Among authors: venkatesan r. J Phys Chem B. 2012 Mar 22;116(11):3619-29. doi: 10.1021/jp210185m. Epub 2012 Mar 7. J Phys Chem B. 2012. PMID: 22360758

5

Structure of mycobacterial β-oxidation trifunctional enzyme reveals its altered assembly and putative substrate channeling pathway.

Venkatesan R, Wierenga RK. Venkatesan R, et al. ACS Chem Biol. 2013 May 17;8(5):1063-73. doi: 10.1021/cb400007k. Epub 2013 Mar 27. ACS Chem Biol. 2013. PMID: 23496842

6

Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.

Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z. Venkatesan R, et al. Nat Commun. 2014 Sep 9;5:4805. doi: 10.1038/ncomms5805. Nat Commun. 2014. PMID: 25203508 Free article.

7

The first case in Asia of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (HSD10 disease) with atypical presentation.

Fukao T, Akiba K, Goto M, Kuwayama N, Morita M, Hori T, Aoyama Y, Venkatesan R, Wierenga R, Moriyama Y, Hashimoto T, Usuda N, Murayama K, Ohtake A, Hasegawa Y, Shigematsu Y, Hasegawa Y. Fukao T, et al. Among authors: venkatesan r. J Hum Genet. 2014 Nov;59(11):609-14. doi: 10.1038/jhg.2014.79. Epub 2014 Sep 18. J Hum Genet. 2014. PMID: 25231369

8

Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic β-oxidation trifunctional enzyme complexes.

Sah-Teli SK, Hynönen MJ, Schmitz W, Geraets JA, Seitsonen J, Pedersen JS, Butcher SJ, Wierenga RK, Venkatesan R. Sah-Teli SK, et al. Among authors: venkatesan r. Biochem J. 2019 Jul 15;476(13):1975-1994. doi: 10.1042/BCJ20190314. Biochem J. 2019. PMID: 31235482

9

Insights into the stability and substrate specificity of the E. coli aerobic β-oxidation trifunctional enzyme complex.

Sah-Teli SK, Hynönen MJ, Sulu R, Dalwani S, Schmitz W, Wierenga RK, Venkatesan R. Sah-Teli SK, et al. Among authors: venkatesan r. J Struct Biol. 2020 Jun 1;210(3):107494. doi: 10.1016/j.jsb.2020.107494. Epub 2020 Mar 11. J Struct Biol. 2020. PMID: 32171906

10

Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.

Sridhar S, Schmitz W, Hiltunen JK, Venkatesan R, Bergmann U, Kiema TR, Wierenga RK. Sridhar S, et al. Among authors: venkatesan r. Acta Crystallogr D Struct Biol. 2020 Dec 1;76(Pt 12):1256-1269. doi: 10.1107/S2059798320013819. Epub 2020 Nov 24. Acta Crystallogr D Struct Biol. 2020. PMID: 33263331

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