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Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
Penack O, Henke E, Suh D, King CG, Smith OM, Na IK, Holland AM, Ghosh A, Lu SX, Jenq RR, Liu C, Murphy GF, Lu TT, May C, Scheinberg DA, Gao DC, Mittal V, Heller G, Benezra R, van den Brink MR. Penack O, et al. Among authors: van den brink mr. J Natl Cancer Inst. 2010 Jun 16;102(12):894-908. doi: 10.1093/jnci/djq172. Epub 2010 May 12. J Natl Cancer Inst. 2010. PMID: 20463307 Free PMC article.
T cells require TRAIL for optimal graft-versus-tumor activity.
Schmaltz C, Alpdogan O, Kappel BJ, Muriglan SJ, Rotolo JA, Ongchin J, Willis LM, Greenberg AS, Eng JM, Crawford JM, Murphy GF, Yagita H, Walczak H, Peschon JJ, van den Brink MR. Schmaltz C, et al. Among authors: van den brink mr. Nat Med. 2002 Dec;8(12):1433-7. doi: 10.1038/nm1202-797. Epub 2002 Nov 11. Nat Med. 2002. PMID: 12426560
Kinetics of gene expression in murine cutaneous graft-versus-host disease.
Sugerman PB, Faber SB, Willis LM, Petrovic A, Murphy GF, Pappo J, Silberstein D, van den Brink MR. Sugerman PB, et al. Among authors: van den brink mr. Am J Pathol. 2004 Jun;164(6):2189-202. doi: 10.1016/S0002-9440(10)63776-5. Am J Pathol. 2004. PMID: 15161652 Free PMC article.
Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model.
Friedman JS, Alpdogan O, van den Brink MR, Liu C, Hurwitz D, Boyd A, Kupper TS, Burakoff SJ. Friedman JS, et al. Among authors: van den brink mr. Biol Blood Marrow Transplant. 2004 Jul;10(7):448-60. doi: 10.1016/j.bbmt.2004.03.005. Biol Blood Marrow Transplant. 2004. PMID: 15205666 Free article.
Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation.
Hubbard VM, Eng JM, Ramirez-Montagut T, Tjoe KH, Muriglan SJ, Kochman AA, Terwey TH, Willis LM, Schiro R, Heller G, Murphy GF, Liu C, Alpdogan O, van den Brink MR. Hubbard VM, et al. Among authors: van den brink mr. Blood. 2005 Nov 1;106(9):3285-92. doi: 10.1182/blood-2005-01-0410. Epub 2005 Jun 14. Blood. 2005. PMID: 15956289 Free PMC article.
301 results