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Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema.
Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, Thimmulappa RK, Rangasamy T, Sussan T, Cosgrove G, Mouded M, Shapiro SD, Petrache I, Biswal S, Feinstein E, Tuder RM. Yoshida T, et al. Among authors: perez m. Nat Med. 2010 Jul;16(7):767-73. doi: 10.1038/nm.2157. Epub 2010 May 16. Nat Med. 2010. PMID: 20473305 Free PMC article.
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.
Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, Douglas IS, Pearse DB, Tuder RM. Schmidt EP, et al. Among authors: perez mj. Nat Med. 2012 Aug;18(8):1217-23. doi: 10.1038/nm.2843. Epub 2012 Jul 22. Nat Med. 2012. PMID: 22820644 Free PMC article.
Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation.
Nadon AM, Perez MJ, Hernandez-Saavedra D, Smith LP, Yang Y, Sanders LA, Gandjeva A, Chabon J, Koyanagi DE, Graham BB, Tuder RM, Schmidt EP. Nadon AM, et al. Among authors: perez mj. Am J Pathol. 2014 Sep;184(9):2382-9. doi: 10.1016/j.ajpath.2014.06.002. Epub 2014 Jul 9. Am J Pathol. 2014. PMID: 25016184 Free PMC article.
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM. Lee MH, et al. Among authors: perez mj. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1;323(3):L355-L371. doi: 10.1152/ajplung.00039.2022. Epub 2022 Jun 28. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35763400 Free PMC article.
Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease.
Hunt JM, Bethea B, Liu X, Gandjeva A, Mammen PP, Stacher E, Gandjeva MR, Parish E, Perez M, Smith L, Graham BB, Kuebler WM, Tuder RM. Hunt JM, et al. Among authors: perez m. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15;305(10):L725-36. doi: 10.1152/ajplung.00186.2013. Epub 2013 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 24039255 Free PMC article.
Heparanase mediates renal dysfunction during early sepsis in mice.
Lygizos MI, Yang Y, Altmann CJ, Okamura K, Hernando AA, Perez MJ, Smith LP, Koyanagi DE, Gandjeva A, Bhargava R, Tuder RM, Faubel S, Schmidt EP. Lygizos MI, et al. Among authors: perez mj. Physiol Rep. 2013 Nov;1(6):e00153. doi: 10.1002/phy2.153. Epub 2013 Nov 11. Physiol Rep. 2013. PMID: 24400155 Free PMC article.
5,585 results