Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.
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Ceccherini-Silberstein F, et al. Among authors: pollicita m.
Antimicrob Agents Chemother. 2010 Sep;54(9):3938-48. doi: 10.1128/AAC.01720-09. Epub 2010 May 17.
Antimicrob Agents Chemother. 2010.
PMID: 20479206
Free PMC article.