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Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline.
De Schrijver JM, De Leeneer K, Lefever S, Sabbe N, Pattyn F, Van Nieuwerburgh F, Coucke P, Deforce D, Vandesompele J, Bekaert S, Hellemans J, Van Criekinge W. De Schrijver JM, et al. Among authors: de leeneer k. BMC Bioinformatics. 2010 May 20;11:269. doi: 10.1186/1471-2105-11-269. BMC Bioinformatics. 2010. PMID: 20487544 Free PMC article.
Applying massive parallel sequencing to molecular diagnosis of Marfan and Loeys-Dietz syndromes.
Baetens M, Van Laer L, De Leeneer K, Hellemans J, De Schrijver J, Van De Voorde H, Renard M, Dietz H, Lacro RV, Menten B, Van Criekinge W, De Backer J, De Paepe A, Loeys B, Coucke PJ. Baetens M, et al. Among authors: de leeneer k, de paepe a, de backer j, de schrijver j. Hum Mutat. 2011 Sep;32(9):1053-62. doi: 10.1002/humu.21525. Epub 2011 Jul 20. Hum Mutat. 2011. PMID: 21542060
Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics.
De Leeneer K, De Schrijver J, Clement L, Baetens M, Lefever S, De Keulenaer S, Van Criekinge W, Deforce D, Van Nieuwerburgh F, Bekaert S, Pattyn F, De Wilde B, Coucke P, Vandesompele J, Claes K, Hellemans J. De Leeneer K, et al. Among authors: de wilde b, de keulenaer s, de schrijver j. PLoS One. 2011;6(9):e25531. doi: 10.1371/journal.pone.0025531. Epub 2011 Sep 30. PLoS One. 2011. PMID: 21980484 Free PMC article.
Flexible, scalable, and efficient targeted resequencing on a benchtop sequencer for variant detection in clinical practice.
De Leeneer K, Hellemans J, Steyaert W, Lefever S, Vereecke I, Debals E, Crombez B, Baetens M, Van Heetvelde M, Coppieters F, Vandesompele J, De Jaegher A, De Baere E, Coucke P, Claes K. De Leeneer K, et al. Among authors: de jaegher a, de baere e. Hum Mutat. 2015 Mar;36(3):379-87. doi: 10.1002/humu.22739. Hum Mutat. 2015. PMID: 25504618
Targeted resequencing and variant validation using pxlence PCR assays.
Coppieters F, Verniers K, De Leeneer K, Vandesompele J, Lefever S. Coppieters F, et al. Among authors: de leeneer k. Biomol Detect Quantif. 2015 Oct 9;6:22-6. doi: 10.1016/j.bdq.2015.09.001. eCollection 2016 Jan. Biomol Detect Quantif. 2015. PMID: 27077044 Free PMC article.
Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits.
Van Heetvelde M, Van Bockstal M, Poppe B, Lambein K, Rosseel T, Atanesyan L, Deforce D, Van Den Berghe I, De Leeneer K, Van Dorpe J, Vral A, Claes KBM. Van Heetvelde M, et al. Among authors: de leeneer k. Cancer Lett. 2018 Jul 1;425:125-133. doi: 10.1016/j.canlet.2018.03.026. Epub 2018 Mar 23. Cancer Lett. 2018. PMID: 29580810
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