Flores JM - Search Results

1

TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice.

Tejera AM, Stagno d'Alcontres M, Thanasoula M, Marion RM, Martinez P, Liao C, Flores JM, Tarsounas M, Blasco MA. Tejera AM, et al. Among authors: flores jm. Dev Cell. 2010 May 18;18(5):775-89. doi: 10.1016/j.devcel.2010.03.011. Dev Cell. 2010. PMID: 20493811 Free PMC article.

2

The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.

Cayuela ML, Flores JM, Blasco MA. Cayuela ML, et al. Among authors: flores jm. EMBO Rep. 2005 Mar;6(3):268-74. doi: 10.1038/sj.embor.7400359. EMBO Rep. 2005. PMID: 15731767 Free PMC article.

3

MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres.

Martinez P, Siegl-Cachedenier I, Flores JM, Blasco MA. Martinez P, et al. Among authors: flores jm. Aging Cell. 2009 Feb;8(1):2-17. doi: 10.1111/j.1474-9726.2008.00441.x. Aging Cell. 2009. PMID: 18986375 Free article.

4

Telomerase reverse transcriptase delays aging in cancer-resistant mice.

Tomás-Loba A, Flores I, Fernández-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borrás C, Matheu A, Klatt P, Flores JM, Viña J, Serrano M, Blasco MA. Tomás-Loba A, et al. Among authors: flores i, flores jm. Cell. 2008 Nov 14;135(4):609-22. doi: 10.1016/j.cell.2008.09.034. Cell. 2008. PMID: 19013273 Free article.

5

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.

Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Martínez P, et al. Among authors: flores jm. Genes Dev. 2009 Sep 1;23(17):2060-75. doi: 10.1101/gad.543509. Epub 2009 Aug 13. Genes Dev. 2009. PMID: 19679647 Free PMC article.

6

53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.

Martínez P, Flores JM, Blasco MA. Martínez P, et al. Among authors: flores jm. J Cell Biol. 2012 Apr 16;197(2):283-300. doi: 10.1083/jcb.201110124. J Cell Biol. 2012. PMID: 22508511 Free PMC article.

7

RAP1 protects from obesity through its extratelomeric role regulating gene expression.

Martínez P, Gómez-López G, García F, Mercken E, Mitchell S, Flores JM, de Cabo R, Blasco MA. Martínez P, et al. Among authors: flores jm. Cell Rep. 2013 Jun 27;3(6):2059-74. doi: 10.1016/j.celrep.2013.05.030. Epub 2013 Jun 20. Cell Rep. 2013. PMID: 23791526 Free PMC article.

8

Essential role for the TRF2 telomere protein in adult skin homeostasis.

Martínez P, Ferrara-Romeo I, Flores JM, Blasco MA. Martínez P, et al. Among authors: flores jm. Aging Cell. 2014 Aug;13(4):656-68. doi: 10.1111/acel.12221. Epub 2014 Apr 14. Aging Cell. 2014. PMID: 24725274 Free PMC article.

9

In vivo role of checkpoint kinase 2 in signaling telomere dysfunction.

García-Beccaria M, Martínez P, Flores JM, Blasco MA. García-Beccaria M, et al. Among authors: flores jm. Aging Cell. 2014 Oct;13(5):810-6. doi: 10.1111/acel.12237. Epub 2014 Jun 12. Aging Cell. 2014. PMID: 24920220 Free PMC article.

10

Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction.

Povedano JM, Martinez P, Flores JM, Mulero F, Blasco MA. Povedano JM, et al. Among authors: flores jm. Cell Rep. 2015 Jul 14;12(2):286-99. doi: 10.1016/j.celrep.2015.06.028. Epub 2015 Jul 2. Cell Rep. 2015. PMID: 26146081 Free article.

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