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Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer.
Balagurunathan Y, Morse DL, Hostetter G, Shanmugam V, Stafford P, Shack S, Pearson J, Trissal M, Demeure MJ, Von Hoff DD, Hruby VJ, Gillies RJ, Han H. Balagurunathan Y, et al. Among authors: han h. Mol Cancer Ther. 2008 Sep;7(9):3071-80. doi: 10.1158/1535-7163.MCT-08-0402. Epub 2008 Sep 2. Mol Cancer Ther. 2008. PMID: 18765825 Free PMC article.
Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.
Warner SL, Stephens BJ, Nwokenkwo S, Hostetter G, Sugeng A, Hidalgo M, Trent JM, Han H, Von Hoff DD. Warner SL, et al. Among authors: han h. Clin Cancer Res. 2009 Nov 1;15(21):6519-28. doi: 10.1158/1078-0432.CCR-09-0077. Epub 2009 Oct 27. Clin Cancer Res. 2009. PMID: 19861455 Free PMC article.
Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.
Liang WS, Craig DW, Carpten J, Borad MJ, Demeure MJ, Weiss GJ, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Barrett M, Phillips L, Benson H, Tembe W, Braggio E, Kiefer JA, Legendre C, Posner R, Hostetter GH, Baker A, Egan JB, Han H, Lake D, Stites EC, Ramanathan RK, Fonseca R, Stewart AK, Von Hoff D. Liang WS, et al. Among authors: han h. PLoS One. 2012;7(10):e43192. doi: 10.1371/journal.pone.0043192. Epub 2012 Oct 10. PLoS One. 2012. PMID: 23071490 Free PMC article.
Hitting multiple targets with multimeric ligands.
Handl HL, Vagner J, Han H, Mash E, Hruby VJ, Gillies RJ. Handl HL, et al. Among authors: han h. Expert Opin Ther Targets. 2004 Dec;8(6):565-86. doi: 10.1517/14728222.8.6.565. Expert Opin Ther Targets. 2004. PMID: 15584863 Review.
Enhanced targeting with heterobivalent ligands.
Xu L, Vagner J, Josan J, Lynch RM, Morse DL, Baggett B, Han H, Mash EA, Hruby VJ, Gillies RJ. Xu L, et al. Among authors: han h. Mol Cancer Ther. 2009 Aug;8(8):2356-65. doi: 10.1158/1535-7163.MCT-08-1183. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671749 Free PMC article.
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