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Page 1
Over-expression of ST3Gal-I promotes mammary tumorigenesis.
Picco G, Julien S, Brockhausen I, Beatson R, Antonopoulos A, Haslam S, Mandel U, Dell A, Pinder S, Taylor-Papadimitriou J, Burchell J. Picco G, et al. Among authors: mandel u. Glycobiology. 2010 Oct;20(10):1241-50. doi: 10.1093/glycob/cwq085. Epub 2010 Jun 8. Glycobiology. 2010. PMID: 20534593 Free PMC article.
Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.
Sørensen AL, Reis CA, Tarp MA, Mandel U, Ramachandran K, Sankaranarayanan V, Schwientek T, Graham R, Taylor-Papadimitriou J, Hollingsworth MA, Burchell J, Clausen H. Sørensen AL, et al. Among authors: mandel u. Glycobiology. 2006 Feb;16(2):96-107. doi: 10.1093/glycob/cwj044. Epub 2005 Oct 5. Glycobiology. 2006. PMID: 16207894
Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat.
Tarp MA, Sørensen AL, Mandel U, Paulsen H, Burchell J, Taylor-Papadimitriou J, Clausen H. Tarp MA, et al. Among authors: mandel u. Glycobiology. 2007 Feb;17(2):197-209. doi: 10.1093/glycob/cwl061. Epub 2006 Oct 18. Glycobiology. 2007. PMID: 17050588
We have recently shown that MUC1 with GalNAcalpha1-O-Ser/Thr (Tn) and NeuAcalpha2-6GalNAcalpha1-O-Ser/Thr (STn) O-glycosylation is a cancer-specific glycoform, and that Tn/STn-MUC1 glycopeptide-based vaccines can override tolerance in human MUC1 transgenic mice and induce humoral …
We have recently shown that MUC1 with GalNAcalpha1-O-Ser/Thr (Tn) and NeuAcalpha2-6GalNAcalpha1-O-Ser/Thr (STn) O-glycosylation is a cancer- …
The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.
Beatson R, Maurstad G, Picco G, Arulappu A, Coleman J, Wandell HH, Clausen H, Mandel U, Taylor-Papadimitriou J, Sletmoen M, Burchell JM. Beatson R, et al. Among authors: mandel u. PLoS One. 2015 May 7;10(5):e0125994. doi: 10.1371/journal.pone.0125994. eCollection 2015. PLoS One. 2015. PMID: 25951175 Free PMC article.
Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype.
Beatson R, Graham R, Grundland Freile F, Cozzetto D, Kannambath S, Pfeifer E, Woodman N, Owen J, Nuamah R, Mandel U, Pinder S, Gillett C, Noll T, Bouybayoune I, Taylor-Papadimitriou J, Burchell JM. Beatson R, et al. Among authors: mandel u. Commun Biol. 2020 Nov 4;3(1):644. doi: 10.1038/s42003-020-01359-5. Commun Biol. 2020. PMID: 33149188 Free PMC article.
Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes.
Wandall HH, Blixt O, Tarp MA, Pedersen JW, Bennett EP, Mandel U, Ragupathi G, Livingston PO, Hollingsworth MA, Taylor-Papadimitriou J, Burchell J, Clausen H. Wandall HH, et al. Among authors: mandel u. Cancer Res. 2010 Feb 15;70(4):1306-13. doi: 10.1158/0008-5472.CAN-09-2893. Epub 2010 Feb 2. Cancer Res. 2010. PMID: 20124478 Free PMC article.
Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells.
Napoletano C, Rughetti A, Agervig Tarp MP, Coleman J, Bennett EP, Picco G, Sale P, Denda-Nagai K, Irimura T, Mandel U, Clausen H, Frati L, Taylor-Papadimitriou J, Burchell J, Nuti M. Napoletano C, et al. Among authors: mandel u. Cancer Res. 2007 Sep 1;67(17):8358-67. doi: 10.1158/0008-5472.CAN-07-1035. Cancer Res. 2007. PMID: 17804752 Free article.
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.
Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA. Marcos NT, et al. Among authors: mandel u. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1443-55. doi: 10.2741/e345. Front Biosci (Elite Ed). 2011. PMID: 21622148 Free article.
128 results