Rais RH - Search Results

1

Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: biological activities and selective toxicities.

Al Safarjalani ON, Rais RH, Kim YA, Chu CK, Naguib FN, El Kouni MH. Al Safarjalani ON, et al. Among authors: rais rh. Biochem Pharmacol. 2010 Oct 1;80(7):955-63. doi: 10.1016/j.bcp.2010.06.001. Epub 2010 Jun 10. Biochem Pharmacol. 2010. PMID: 20541538 Free PMC article.

2

Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.

Al Safarjalani ON, Rais R, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1449-55. doi: 10.1007/s00280-012-1842-x. Epub 2012 Feb 29. Cancer Chemother Pharmacol. 2012. PMID: 22373605

3

Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

Yadav V, Chu CK, Rais RH, Al Safarjalani ON, Guarcello V, Naguib FN, el Kouni MH. Yadav V, et al. Among authors: rais rh. J Med Chem. 2004 Apr 8;47(8):1987-96. doi: 10.1021/jm030537y. J Med Chem. 2004. PMID: 15055998

4

6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

Rais RH, Al Safarjalani ON, Yadav V, Guarcello V, Kirk M, Chu CK, Naguib FN, el Kouni MH. Rais RH, et al. Biochem Pharmacol. 2005 May 15;69(10):1409-19. doi: 10.1016/j.bcp.2005.02.017. Biochem Pharmacol. 2005. PMID: 15857605

5

Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.

Kim YA, Sharon A, Chu CK, Rais RH, Al Safarjalani ON, Naguib FN, el Kouni MH. Kim YA, et al. Among authors: rais rh. Biochem Pharmacol. 2007 May 15;73(10):1558-72. doi: 10.1016/j.bcp.2007.01.026. Epub 2007 Jan 21. Biochem Pharmacol. 2007. PMID: 17306769 Free PMC article.

6

Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase.

Kim YA, Sharon A, Chu CK, Rais RH, Al Safarjalani ON, Naguib FN, el Kouni MH. Kim YA, et al. Among authors: rais rh. J Med Chem. 2008 Jul 10;51(13):3934-45. doi: 10.1021/jm800201s. Epub 2008 Jun 19. J Med Chem. 2008. PMID: 18563892

7

7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

Al Safarjalani ON, Rais RH, Kim YA, Chu CK, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Among authors: rais rh. Biochem Pharmacol. 2008 Oct 15;76(8):958-66. doi: 10.1016/j.bcp.2008.07.035. Epub 2008 Aug 7. Biochem Pharmacol. 2008. PMID: 18755159 Free PMC article.

8

Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

Kim YA, Rawal RK, Yoo J, Sharon A, Jha AK, Chu CK, Rais RH, Al Safarjalani ON, Naguib FN, El Kouni MH. Kim YA, et al. Among authors: rais rh. Bioorg Med Chem. 2010 May 15;18(10):3403-12. doi: 10.1016/j.bmc.2010.04.003. Epub 2010 Apr 8. Bioorg Med Chem. 2010. PMID: 20456959

9

Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine.

Naguib FN, Rais RH, Al Safarjalani ON, el Kouni MH. Naguib FN, et al. Among authors: rais rh. Comp Biochem Physiol B Biochem Mol Biol. 2015 Oct;188:63-9. doi: 10.1016/j.cbpb.2015.06.006. Epub 2015 Jun 23. Comp Biochem Physiol B Biochem Mol Biol. 2015. PMID: 26112826 Free PMC article.

10

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.

Al Safarjalani ON, Rais R, Shi J, Schinazi RF, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2006 Nov;58(5):692-8. doi: 10.1007/s00280-006-0213-x. Epub 2006 Mar 10. Cancer Chemother Pharmacol. 2006. PMID: 16528530

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