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Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism.
Yabut KCB, Martynova A, Nath A, Zercher BP, Bush MF, Isoherranen N. Yabut KCB, et al. Among authors: isoherranen n. bioRxiv [Preprint]. 2024 Jan 19:2024.01.17.576032. doi: 10.1101/2024.01.17.576032. bioRxiv. 2024. Update in: Mol Pharmacol. 2024 May 17;105(6):395-410. doi: 10.1124/molpharm.124.000878 PMID: 38293009 Free PMC article. Updated. Preprint.
Role of itraconazole metabolites in CYP3A4 inhibition.
Isoherranen N, Kunze KL, Allen KE, Nelson WL, Thummel KE. Isoherranen N, et al. Drug Metab Dispos. 2004 Oct;32(10):1121-31. doi: 10.1124/dmd.104.000315. Epub 2004 Jul 8. Drug Metab Dispos. 2004. PMID: 15242978
Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.
Huang W, Lin YS, McConn DJ 2nd, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE. Huang W, et al. Among authors: isoherranen n. Drug Metab Dispos. 2004 Dec;32(12):1434-45. doi: 10.1124/dmd.104.001313. Epub 2004 Sep 21. Drug Metab Dispos. 2004. PMID: 15383492
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
Kunze KL, Nelson WL, Kharasch ED, Thummel KE, Isoherranen N. Kunze KL, et al. Among authors: isoherranen n. Drug Metab Dispos. 2006 Apr;34(4):583-90. doi: 10.1124/dmd.105.008508. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415110 Clinical Trial.
The role of CYP26 enzymes in retinoic acid clearance.
Thatcher JE, Isoherranen N. Thatcher JE, et al. Among authors: isoherranen n. Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):875-86. doi: 10.1517/17425250903032681. Expert Opin Drug Metab Toxicol. 2009. PMID: 19519282 Free PMC article. Review.
171 results