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Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.
Rank L, Veith S, Gwosch EC, Demgenski J, Ganz M, Jongmans MC, Vogel C, Fischbach A, Buerger S, Fischer JM, Zubel T, Stier A, Renner C, Schmalz M, Beneke S, Groettrup M, Kuiper RP, Bürkle A, Ferrando-May E, Mangerich A. Rank L, et al. Among authors: fischbach a. Nucleic Acids Res. 2016 Dec 1;44(21):10386-10405. doi: 10.1093/nar/gkw859. Epub 2016 Sep 29. Nucleic Acids Res. 2016. PMID: 27694308 Free PMC article.
The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.
Fischbach A, Krüger A, Hampp S, Assmann G, Rank L, Hufnagel M, Stöckl MT, Fischer JMF, Veith S, Rossatti P, Ganz M, Ferrando-May E, Hartwig A, Hauser K, Wiesmüller L, Bürkle A, Mangerich A. Fischbach A, et al. Nucleic Acids Res. 2018 Jan 25;46(2):804-822. doi: 10.1093/nar/gkx1205. Nucleic Acids Res. 2018. PMID: 29216372 Free PMC article.
Restriction of AID activity and somatic hypermutation by PARP-1.
Tepper S, Mortusewicz O, Członka E, Bello A, Schmidt A, Jeschke J, Fischbach A, Pfeil I, Petersen-Mahrt SK, Mangerich A, Helleday T, Leonhardt H, Jungnickel B. Tepper S, et al. Among authors: fischbach a. Nucleic Acids Res. 2019 Aug 22;47(14):7418-7429. doi: 10.1093/nar/gkz466. Nucleic Acids Res. 2019. PMID: 31127309 Free PMC article.
88 results